Author + information
- Received January 10, 1986
- Revision received March 13, 1986
- Accepted May 21, 1986
- Published online October 1, 1986.
- David E. Guyer, MD, FACC1,
- Rodney A. Foale, MBBS1,
- Linda D. Gillam, MD, FACC1,
- Gerard T. Wilkins, MB, ChB1,2,
- J. Luis Guerrero1 and
- Arthur E. Weyman, MD, FACC*,1
- ↵*Address for reprints: Arthur E. Weyman, MD, Massachusetts General Hospital, Cardiac Non-Invasive Laboratory, Fruit Street, Boston, Massachusetts 02114.
A convenient noninvasive method of mapping the left ventricular endocardial surface has been developed that can be used to display regional dysfunction and calculate the total area of abnormal endocardial excursion from data obtained in two orthogonal apical and three or more short-axis cross-sectional echocardiographic images. Visually identified regions of abnormal systolic function are plotted on end-diastolic, planar endocardial surface maps, and the extent of dysfunction can be expressed either as an absolute area or as a fraction of the total endocardial surface area involved. The extent of the left ventricular surface moving abnormally, calculated with this echocardiographic mapping technique, was compared with two histochemical measures of infarct size in a series of 11 closed chest dogs with acute circumflex coronary artery occlusions. Overall extent of abnormally moving left ventricular wall correlated closely with both the fraction of the endocardial area overlying infarct (r = 0.92, p ≤ 0.001) and the fraction of the myocardial volume infarcted (r = 0.86, p ≤ 0.001). This suggests that the echocardiographic mapping technique can be used to accurately quantify the global extent of abnormal systolic function in the presence of regional wall motion abnormalities.
- Received January 10, 1986.
- Revision received March 13, 1986.
- Accepted May 21, 1986.
- American College of Cardiology Foundation