Journal of the American College of Cardiology
Idiopathic lymphoplasmacytic aortic valvulitis: Observations in two elderly women with unexplained aortic insufficiency
Author + information
- Randall S. Vollertsen, MD*,1,
- William D. Edwards, MD, FACC1,
- Robert E. Safford, MD, PhD, FACC1 and
- Michael J. Osborn, MD, FACC1
- ↵*Address for reprints: Randall S. Vollertsen, MD, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905.
Abstract
Two patients with a unique aortic valvulitis required aortic valve replacement. Both were elderly women who presented with evidence of systemic disease, including fever, arthralgia, myalgia, markedly elevated erythrocyte sedimentation rate, anemia, leukbcytosis, hypoalbumihemia and renal insufficiency, in addition to progressive subacute aortic insufficiency. Histologic examination of the excised aortic valve revealed a lymphoplasmacytic infiltrate. Neither patient had evidence of other diseases that have been associated with aortic insufficiency. One should consider the judicious use of glucocorticosteroids for such patients.
- Received February 18, 1986.
- Revision received May 19, 1986.
- Accepted June 6, 1986.
- American College of Cardiology Foundation
