RT Journal Article SR Electronic T1 Focal Atrial Tachycardia Originating From the Non-Coronary Aortic Sinus JF Journal of the American College of Cardiology FD American College of Cardiology SP 122 OP 131 DO 10.1016/j.jacc.2006.02.053 VO 48 IS 1 A1 Ouyang, Feifan A1 Ma, Jian A1 Ho, Siew Yen A1 Bänsch, Dietmar A1 Schmidt, Boris A1 Ernst, Sabine A1 Kuck, Karl-Heinz A1 Liu, Shaowen A1 Huang, He A1 Chen, Min A1 Chun, Julian A1 Xia, Yunlong A1 Satomi, Kazuhiro A1 Chu, Huimin A1 Zhang, Shu A1 Antz, Matthias YR 2006 UL http://www.onlinejacc.org/content/48/1/122.abstract AB Focal Atrial Tachycardia Originating From the Non-Coronary Aortic Sinus: Electrophysiological Characteristics and Catheter AblationFeifan Ouyang, Jian Ma, Siew Yen Ho, Dietmar Bänsch, Boris Schmidt, Sabine Ernst, Karl-Heinz Kuck, Shaowen Liu, He Huang, Min Chen, Julian Chun, Yunlong Xia, Kazuhiro Satomi, Huimin Chu, Shu Zhang, Matthias AntzIn 9 patients with focal atrial tachycardia (AT) originating from the non-coronary aortic sinus (AS), mapping in the aorta demonstrated that an earliest atrial activation preceded the atrial activation at the His bundle (HB) by 12.2 ± 6.9 ms. Also, the His potentials were not found at the successful site in the non-coronary AS. The focal AT was terminated in <8 s with radiofrequency application in all 9 patients. No procedure-related complications occurred. All 9 patients were free of arrhythmias without antiarrhythmic drugs during a follow-up of 9 ± 3 months. In patients with focal AT near the HB region, mapping in the non-coronary AS can improve clinical outcome.Objectives We sought to investigate electrophysiological characteristics and catheter ablation in patients with focal atrial tachycardia (AT) originating from the non-coronary aortic sinus (AS).Background In patients with failed ablation of focal AT near the His bundle (HB) region, an origin from the non-coronary AS should be considered because of the close anatomical relationship.Methods This study included 9 patients with focal AT, in 6 of whom attempted radiofrequency (RF) ablation had previously failed. Activation mapping was performed during tachycardia to identify an earliest activation in the atria and the AS. The aortic root angiography was performed to identify the origin in the AS before RF ablation.Results Focal AT was reproducibly induced by atrial pacing. Mapping in atria demonstrated that the earliest atrial activation was located at the HB region, whereas mapping in the non-coronary AS demonstrated that an earliest atrial activation preceded the atrial activation at the HB by 12.2 ± 6.9 ms and was anatomically located superoposterior to the HB in all 9 patients. Also, His potentials were not found at the successful site in the non-coronary AS in all 9 patients. The focal AT was terminated in <8 s in all 9 patients. Junctional beats and PR prolongation did not occur during RF application in all 9 patients. No complications occurred in any of the nine patients. All 9 patients were free of arrhythmias without antiarrhythmic drugs during a follow-up of 9 ± 3 months.Conclusions In patients with focal AT near the HB region, mapping in the non-coronary AS can improve clinical outcome.