RT Journal Article
SR Electronic
T1 Pacemaker Implantation After Mitral Valve Surgery With Atrial Fibrillation Ablation
JF Journal of the American College of Cardiology
FD American College of Cardiology
SP 2427
OP 2435
DO 10.1016/j.jacc.2019.02.062
VO 73
IS 19
A1 DeRose, Joseph J.
A1 Mancini, Donna M.
A1 Chang, Helena L.
A1 Argenziano, Michael
A1 Dagenais, François
A1 Ailawadi, Gorav
A1 Perrault, Louis P.
A1 Parides, Michael K.
A1 Taddei-Peters, Wendy C.
A1 Mack, Michael J.
A1 Glower, Donald D.
A1 Yerokun, Babatunde A.
A1 Atluri, Pavan
A1 Mullen, John C.
A1 Puskas, John D.
A1 O’Sullivan, Karen
A1 Sledz, Nancy M.
A1 Tremblay, Hugo
A1 Moquete, Ellen
A1 Ferket, Bart S.
A1 Moskowitz, Alan J.
A1 Iribarne, Alexander
A1 Gelijns, Annetine C.
A1 O’Gara, Patrick T.
A1 Blackstone, Eugene H.
A1 Gillinov, A. Marc
A1 ,
A1 Miller, Marissa A.
A1 Taddei-Peters, Wendy C.
A1 Buxton, Dennis
A1 Connolly, Amy
A1 Geller, Nancy L.
A1 Gordon, David
A1 Jeffries, Neal O.
A1 Lee, Albert
A1 Moy, Claudia S.
A1 Gombos, Ilana Kogan
A1 Ralph, Jennifer
A1 Weisel, Richard
A1 Gardner, Timothy J.
A1 O’Gara, Patrick T.
A1 Rose, Eric A.
A1 Gelijns, Annetine C.
A1 Parides, Michael K.
A1 Ascheim, Deborah D.
A1 Moskowitz, Alan J.
A1 Bagiella, Emilia
A1 Moquete, Ellen
A1 Chang, Helena
A1 Chase, Melissa
A1 Dobrev, Edlira
A1 Goldfarb, Seth
A1 Gupta, Lopa
A1 Kirkwood, Katherine
A1 Levitan, Ron
A1 O’Sullivan, Karen
A1 Overbey, Jessica
A1 Santos, Milerva
A1 Weglinski, Michael
A1 Williams, Paula
A1 Wood, Carrie
A1 Ye, Xia
A1 Mack, Michael
A1 Adame, Tracine
A1 Settele, Natalie
A1 Adams, Jenny
A1 Ryan, William
A1 Smith, Robert L.
A1 Grayburn, Paul
A1 Chen, Frederick Y.
A1 Nohria, Anju
A1 Cohn, Lawrence
A1 Shekar, Prem
A1 Aranki, Sary
A1 Couper, Gregory
A1 Davidson, Michael
A1 Bolman, R. Morton
A1 Burgess, Anne
A1 Conboy, Debra
A1 Blackwell, Ray
A1 Kerzner, Roger
A1 Banbury, Michael
A1 Squire, Andrea M.
A1 Gillinov, A. Marc
A1 Blackstone, Eugene H.
A1 Lytle, Bruce
A1 Mihaljevic, Tomislav
A1 Lackner, Pamela
A1 Berroteran, Leoma
A1 Dolney, Diana
A1 Fleming, Suzanne
A1 Palumbo, Roberta
A1 Whitman, Christine
A1 Sankovic, Kathy
A1 Sweeney, Denise Kosty
A1 Pattakos, Gregory
A1 Argenziano, Michael
A1 Williams, Mathew
A1 Goldsmith, Lyn
A1 Smith, Craig R.
A1 Naka, Yoshifumi
A1 Stewart, Allan
A1 Schwartz, Allan
A1 Bell, Daniel
A1 Van Patten, Danielle
A1 Sreekanth, Sowmya
A1 Smith, Peter K.
A1 Alexander, John H.
A1 Milano, Carmelo A.
A1 Glower, Donald D.
A1 Mathew, Joseph P.
A1 Harrison, J. Kevin
A1 Welsh, Stacey
A1 Ferguson, T. Bruce
A1 Kypson, Alan P.
A1 Rodriguez, Evelio
A1 Harris, Malissa
A1 Akers, Brenda
A1 O'Neal, Allison
A1 Puskas, John D.
A1 Thourani, Vinod H.
A1 Guyton, Robert
A1 Baer, Jefferson
A1 Baio, Kim
A1 Neill, Alexis A.
A1 Voisine, Pierre
A1 Senechal, Mario
A1 Dagenais, François
A1 O’Connor, Kim
A1 Dussault, Gladys
A1 Ballivian, Tatiana
A1 Keilani, Suzanne
A1 Michler, Robert E.
A1 D'Alessandro, David A.
A1 DeRose, Joseph J.
A1 Goldstein, Daniel J.
A1 Bello, Ricardo
A1 Jakobleff, William
A1 Garcia, Mario
A1 Taub, Cynthia
A1 Spevack, Daniel
A1 Swayze, Roger
A1 Sookraj, Nadia
A1 Perrault, Louis P.
A1 Basmadjian, Arsène-Joseph
A1 Bouchard, Denis
A1 Carrier, Michel
A1 Cartier, Raymond
A1 Pellerin, Michel
A1 Tanguay, Jean François
A1 El-Hamamsy, Ismael
A1 Denault, André
A1 Lacharité, Jonathan
A1 Robichaud, Sophie
A1 Adams, David H.
A1 Varghese, Robin
A1 Mandel-Portnoy, Yael
A1 Horvath, Keith A.
A1 Corcoran, Philip C.
A1 Siegenthaler, Michael P.
A1 Murphy, Mandy
A1 Iraola, Margaret
A1 Greenberg, Ann
A1 Sai-Sudhakar, Chittoor
A1 Hasan, Ayseha
A1 McDavid, Asia
A1 Kinn, Bradley
A1 Mullen, John C.
A1 Choy, Jonathan
A1 Meyer, Steven
A1 Kuurstra, Emily
A1 Gammie, James S.
A1 DeFilippi, Christopher R.
A1 Gaetani, Dino T.
A1 Young, Cindi A.
A1 Beach, Dana
A1 Collins, Julia
A1 Bolling, Steven F.
A1 Pagani, Francis D.
A1 Bloem, Cathie
A1 Acker, Michael A.
A1 Woo, Y. Joseph
A1 Mayer, Mary Lou
A1 Bavaria, Joseph E.
A1 Szeto, Wilson Y.
A1 Margulies, Kenneth
A1 Keane, Martin
A1 Glassberg, Helene
A1 Jagasia, Dinesh
A1 Kirkpatrick, James
A1 Kron, Irving L.
A1 Ailawadi, Gorav
A1 Johnston, Karen
A1 Dent, John M.
A1 Kern, John
A1 Keim, Jessica
A1 Burks, Sandra
A1 Gahring, Kim
A1 Mangi, Abeel
A1 Akar, Joseph
A1 Yuh, David
A1 Wilson, Lynn
A1 Bull, David A.
A1 Desvigne-Nickens, Patrice
A1 Dixon, Dennis O.
A1 Haigney, Mark
A1 Holubkov, Richard
A1 Jacobs, Alice
A1 Miller, Frank
A1 Murkin, John M.
A1 Spertus, John
A1 Wechsler, Andrew S.
A1 Sellke, Frank
A1 McDonald, Cheryl L.
A1 Byington, Robert
A1 Dickert, Neal
A1 Dixon, Dennis O.
A1 Ikonomidis, John S.
A1 Williams, David O.
A1 Yancy, Clyde W.
A1 Canty, John M.
A1 Fang, James C.
A1 Giannetti, Nadia
A1 Richenbacher, Wayne
A1 Rao, Vivek
A1 Furie, Karen L.
A1 Miller, Rachel
A1 Pinney, Sean
A1 Roberts, William C.
A1 Walsh, Mary N.
A1 Hung, Judy
A1 Zeng, Xin
A1 Couderc, Jean-Philippe
A1 Balda, Dan
A1 Bowen, Wayne
A1 Wilson, Mauri
A1 Schering, Anne
YR 2019
UL http://www.onlinejacc.org/content/73/19/2427.abstract
AB Background The incidence of permanent pacemaker (PPM) implantation is higher following mitral valve surgery (MVS) with ablation for atrial fibrillation (AF) compared with MVS alone.Objectives This study identified risk factors and outcomes associated with PPM implantation in a randomized trial that evaluated ablation for AF in patients who underwent MVS.Methods A total of 243 patients with AF and without previous PPM placement were randomly assigned to MVS alone (n = 117) or MVS + ablation (n = 126). Patients in the ablation group were further randomized to pulmonary vein isolation (PVI) (n = 62) or the biatrial maze procedure (n = 64). Using competing risk models, this study examined the association among PPM and baseline and operative risk factors, and the effect of PPM on time to discharge, readmissions, and 1-year mortality.Results Thirty-five patients received a PPM within the first year (14.4%), 29 (83%) underwent implantation during the index hospitalization. The frequency of PPM implantation was 7.7% in patients randomized to MVS alone, 16.1% in MVS + PVI, and 25% in MVS + biatrial maze. The indications for PPM were similar among patients who underwent MVS with and without ablation. Ablation, multivalve surgery, and New York Heart Association functional (NYHA) functional class III/IV were independent risk factors for PPM implantation. Length of stay post-surgery was longer in patients who received PPMs, but it was not significant when adjusted for randomization assignment (MVS vs. ablation) and age (hazard ratio [HR]: 0.81; 95% confidence interval [CI]: 0.61 to 1.08; p = 0.14). PPM implantation did not increase 30-day readmission rate (HR: 1.43; 95% CI: 0.50 to 4.05; p = 0.50). The need for PPM was associated with a higher risk of 1-year mortality (HR: 3.21; 95% CI: 1.01 to 10.17; p = 0.05) after adjustment for randomization assignment, age, and NYHA functional class.Conclusions AF ablation, multivalve surgery, and NYHA functional class III/IV were associated with an increased risk for permanent pacing. PPM implantation following MVS was associated with a significant increase in 1-year mortality. (Surgical Ablation Versus No Surgical Ablation for Patients With Atrial Fibrillation Undergoing Mitral Valve Surgery; NCT00903370)