Table 5

Systemic, Coronary, and Microcirculatory Hemodynamic Responses to Exercise Before and After PCI

Pre-PCIPost-PCIp Value (ANOVA)
Baseline1 Mint50 (Expre)Peak (Expre)Baseline1 Mint50 (Expre)Peak (Expre)Peak (Expost)
HR, beats/min67 ± 1383 ± 1885 ± 2283 ± 2066 ± 1283 ± 1785 ± 1686 ± 1788 ± 170.19
SBP, mm Hg142 ± 18152 ± 21160 ± 21151 ± 24140 ± 19158 ± 20159 ± 22165 ± 20163 ± 260.004
RPP9,836 ± 2,35513,069 ± 3,92014,122 ± 4,45812,515 ± 3,6979,405 ± 1,93113,301 ± 2,71013,550 ± 3,14015,603 ± 5,24214,903 ± 3,8970.02
PP, mm Hg62 ± 1165 ± 1065 ± 1366 ± 1358 ± 1265 ± 1166 ± 1073 ± 1274 ± 140.35
TTI, mm Hg · s−144 ± 644 ± 645 ± 744 ± 841 ± 844 ± 845 ± 1046 ± 744 ± 130.68
DTI, mm Hg · s−146 ± 1234 ± 734 ± 832 ± 1146 ± 1535 ± 1033 ± 1236 ± 831 ± 100.90
DTF0.57 ± 0.070.51 ± 0.060.49 ± 0.070.50 ± 0.070.58 ± 0.060.51 ± 0.050.50 ± 0.070.51 ± 0.050.50 ± 0.050.86
APV, cm/s15 ± 518 ± 718 ± 818 ± 817 ± 423 ± 825 ± 1026 ± 730 ± 90.002
SR, mm Hg · cm−1.s−12.7 ± 3.12.60 ± 3.22.7 ± 3.12.8 ± 2.90.19 ± 0.250.21 ± 0.240.21 ± 0.210.24 ± 0.190.21 ± 0.18<0.001
ΔP, mm Hg28 ± 2130 ± 2031 ± 2032 ± 193 ± 44 ± 55 ± 46 ± 55 ± 5<0.001
PdPa0.70 ± 0.220.72 ± 0.190.69 ± 0.180.66 ± 0.190.97 ± 0.040.96 ± 0.040.96 ± 0.040.95 ± 0.040.95 ± 0.05<0.001
Pd, mm Hg69 ± 2376 ± 2475 ± 2566 ± 2491 ± 14101 ± 14100 ± 16102 ± 1798 ± 18<0.001
DMR, mm Hg · cm−1.s−13.0 ± 1.42.4 ± 1.12.1 ± 1.02.3 ± 1.43.9 ± 1.43.6 ± 1.83.3 ± 1.92.9 ± 1.92.2 ± 1.10.007

Values are mean ± SD.

ANOVA = analysis of variance; APV = average peak coronary flow velocity; DMR = diastolic microvascular resistance; ΔP = pressure-gradient; DTI = diastolic time index; DTF = diastolic time fraction; Expost = post-percutaneous coronary intervention exercise time; Expre = pre-percutaneous coronary intervention exercise time; HR = heart rate; PCI = percutaneous coronary intervention; Pd = distal coronary pressure; PdPa = pressure ratio; PP = pulse pressure; RPP = rate-pressure product; SBP = systemic blood pressure; SR = stenosis resistance; t50 = 50% of the exercise time; TTI = tension-time index.