Table 2

Consensus Related to CMR Methodologies for Myocardial Tissue Characterization

Conceptually, the AAR is the myocardium downstream to an occluded coronary artery that becomes ischemic (1).
Infarct size and AAR should be ideally measured at the same time point. If measured at different time points, salvage quantification might show implausible results (e.g., negative values) (14–16,90).
LGE grey zones should not be interpreted as dead, since they likely represent a mixture of bright (dead) and dark (alive) myocardium. Grey myocardium can be due to partial volume effect (15,31).
Edema development should be interpreted as a manifestation of myocardial I/R injury and should not be considered as a reliable marker of AAR (15,44,89).
T1W is the recommended methodology for LGE imaging after MI (2,4).
T2-mapping is the recommended methodology for edema imaging after MI (3,35).
T1W LGE is the recommended methodology for MVO imaging (hypointense areas within the LGE area) (95).
T2∗ mapping is the recommended methodology for IMH imaging after MI (3).

AAR = area at risk; LGE = late gadolinium enhancement; other abbreviations as in Table 1.

  • Controversial topic (majority but not all panelists in agreement).