Table 3

Covariate-Adjusted Independent Predictors of 3-Year Cardiac Mortality

Risk FactorHR (95% CI)p Value
Age (per 5 yrs)1.33 (1.21–1.46)<0.001
White blood cell count (per 109 cells/l)1.14 (1.08–1.20)<0.001
Serum creatinine (per 0.1 mg/dl)1.08 (1.03–1.14)0.003
Killip class 2–41.63 (1.04–2.56)0.03
PCI of the left main artery6.47 (2.30–18.20)<0.001
PCI of the left anterior descending artery1.62 (1.08–2.43)0.02
Diabetes, medically-treated1.51 (1.01–2.25)0.05
Major bleed2.53 (1.61–3.98)<0.001
Acquired thrombocytopenia2.29 (1.49–3.52)<0.001
Reinfarction7.88 (4.62–13.42)<0.001
Bivalirudin (vs. UFH+GPI)0.57 (0.39–0.83)0.003

Other variables in the model that were not significantly associated with cardiac mortality: current smoker, female sex, prior myocardial infarction, number of vessels treated, and baseline hemoglobin. Model excludes 145 patients with thrombocytopenia at baseline.

Abbreviations as in Table 1.

  • Major bleed and reinfarction are fitted as time-updated covariates from the moment they occurred.