Table 4

Per-Patient and Per-Vessel Diagnostic Performance of FFRCT, Coronary CTA, and ICA

Per-PatientPer-Vessel
Coronary CTA Stenosis >50%p ValueFFRCT ≤0.80p ValueICA Stenosis >50%Coronary CTA Stenosis >50%p ValueFFRCT ≤0.80p ValueICA Stenosis >50%
Accuracy53 (47–57)<0.00181 (76–85)0.0977 (71–82)65 (61–69)<0.00186 (83–89)0.03282 (79–86)
Sensitivity94 (86–97)0.05886 (77–92)<0.00164 (53–74)83 (74–89)0.9184 (75–89)<0.00155 (45–65)
Specificity34 (27–41)<0.00179 (72–84)0.2983 (77–88)60 (56–65)<0.00186 (82–89)0.1690 (86–93)
PPV40 (33–47)<0.00165 (56–74)0.3463 (52–73)33 (27–39)<0.00161 (53–69)0.1858 (48–68)
NPV92 (83–97)0.4693 (87–96)<0.00183 (77–89)92 (88–95)0.06895 (93–97)<0.00188 (85–92)

Values are proportion, % (95% CI). FFR ≤0.80 was diagnostic of lesion-specific ischemia. N = 254 subjects and 484 for vessels.

NPV = negative predictive value; PPV = positive predictive value; other abbreviations as in Tables 2 and 3.