Planned Nesiritide | Planned Placebo | p Value | |
---|---|---|---|

eGFR (median 59.5 ml/kg/min) | |||

Below median | 7.72 (7.31, 8.09) | 7.65 (7.31, 8.04) | 0.015 |

Above median | 7.74 (7.38, 8.10) | 7.74 (7.38, 8.13) | 0.560 |

Creatinine (median 1.21 mg/dl) | |||

Below median | 7.72 (7.33, 8.06) | 7.70 (7.37, 8.10) | 0.657 |

Above median | 7.76 (7.38, 8.12) | 7.70 (7.31, 8.07) | 0.024 |

BUN (median 25.06 mg/dl) | |||

Below median | 7.74 (7.35, 8.09) | 7.74 (7.38, 8.13) | 0.418 |

Above median | 7.73 (7.36, 8.10) | 7.65 (7.31, 8.04) | 0.006 |

Previous weight gain | |||

Yes | 7.80 (7.39, 8.16) | 7.77 (7.38, 8.15) | 0.305 |

No | 7.63 (7.30, 7.94) | 7.60 (7.26, 7.94) | 0.479 |

Jugular venous distension | |||

Yes | 7.78 (7.42, 8.12) | 7.76 (7.41, 8.13) | 0.495 |

No | 7.65 (7.28, 8.04) | 7.63 (7.26, 8.01) | 0.229 |

Diastolic BP (median 75 mm Hg) | |||

Below median | 7.70 (7.31, 8.06) | 7.67 (7.31, 8.04) | 0.332 |

Above median | 7.76 (7.38, 8.13) | 7.74 (7.38, 8.15) | 0.354 |

Age (median 66 yrs) | |||

Below median | 7.78 (7.38, 8.13) | 7.74 (7.38, 8.10) | 0.068 |

Above median | 7.69 (7.31, 8.04) | 7.67 (7.31, 8.06) | 0.907 |

BMI (median 27.4 kg/m^{2}) | |||

Below median | 7.66 (7.31, 8.02) | 7.60 (7.28, 7.97) | 0.026 |

Above median | 7.81 (7.04, 8.16) | 7.80 (7.43, 8.19) | 0.788 |

Sex | |||

Male | 7.76 (7.38, 8.13) | 7.74 (7.38, 8.10) | 0.114 |

Female | 7.66 (7.24, 8.01) | 7.64 (7.28, 8.01) | 0.853 |

Values are median (25th, 75th percentile).

eGFR = estimated glomerular filtration rate; other abbreviations as in Table 1.