Table 1

Definition of Clinically Relevant MI After Both PCI and CABG Procedures

1.In patients with normal baseline CK-MBThe peak CK-MB measured within 48 hours of the procedure rises to ≥10 × the local laboratory ULN, or to ≥5 × ULN with new pathologic Q-waves in ≥2 contiguous leads or new persistent LBBB, OR in the absence of CK-MB measurements and a normal baseline cTn, a cTn (I or T) level measured within 48 hours of the PCI rises to ≥70 × the local laboratory ULN, or ≥35 × ULN with new pathologic Q-waves in ≥2 contiguous leads or new persistent LBBB.
2.In patients with elevated baseline CK-MB (or cTn) in whom the biomarker levels are stable or fallingThe CK-MB (or cTn) rises by an absolute increment equal to those levels recommended above from the most recent pre-procedure level.
3.In patients with elevated CK-MB (or cTn) in whom the biomarker levels have not been shown to be stable or fallingThe CK-MB (or cTn) rises by an absolute increment equal to those levels recommended above plus new ST-segment elevation or depression plus signs consistent with a clinically relevant MI, such as new onset or worsening heart failure or sustained hypotension.