Table 3

HRs of All-Cause and Cardiovascular Mortality by Quintile of Weekly Running Time

GroupNonrunners
(0)
Quintile of Running Time, min/week
1
(<51)
2
(51–80)
3
(81–119)
4
(120–175)
5
(≥176)
All-cause mortality
 No. of participants42,1212,7102,5842,5052,6472,570
 No. of deaths2,857110116103112115
 Person-yrs of follow-up602,75241,65342,19741,08240,47340,426
 Death rate45.931.729.729.831.533.8
 Adjusted HR (95% CI)
 Model 11.000.69 (0.57–0.83)0.65 (0.54–0.78)0.65 (0.53–0.79)0.69 (0.57–0.83)0.74 (0.61–0.89)
 Model 21.000.70 (0.58–0.85)0.67 (0.55–0.80)0.67 (0.55–0.82)0.71 (0.58–0.86)0.77 (0.63–0.92)
 Model 3§1.000.80 (0.66–0.97)0.76 (0.63–0.91)0.78 (0.64–0.95)0.84 (0.69–1.02)0.89 (0.74–1.07)
Cardiovascular mortality
 No. of participants40,3192,6282,5012,4352,5672,491
 No. of deaths1,0552833333236
 Person-yrs of follow-up575,35240,49740,76639,98339,27539,233
 Death rate17.88.09.010.39.111.6
 Adjusted HR (95% CI)
 Model 11.000.45 (0.31–0.66)0.50 (0.36–0.71)0.58 (0.41–0.82)0.51 (0.36–0.72)0.65 (0.46–0.91)
 Model 21.000.45 (0.31–0.66)0.52 (0.37–0.73)0.60 (0.42–0.84)0.53 (0.37–0.75)0.67 (0.48–0.93)
 Model 3§1.000.59 (0.40–0.86)0.67 (0.47–0.95)0.82 (0.58–1.16)0.78 (0.54–1.11)0.86 (0.62–1.21)
  • Death rate per 10,000 person-years adjusted for baseline age, sex, and examination year.

  • Model 1 was adjusted for baseline age (years), sex, and examination year.

  • Model 2 was adjusted for model 1 plus smoking status (never, former, or current), alcohol consumption (heavy drinker or not), other physical activities except running (0, 1 to 499, or ≥500 MET-minutes per week), and parental CVD (yes or no).

  • § Model 3 was adjusted for model 2 plus body mass index (kg/m2) and presence or absence of abnormal electrocardiogram, hypertension, diabetes, and hypercholesterolemia.