Table 3

Selected 1-Year Outcomes of MV Repair Versus Replacement for Severe Ischemic MR (From the Cardiothoracic Surgical Trials Network)

MV Repair
(n = 126)
MV Replacement
(n = 125)
p Value
LVESVI (ml/m2; primary endpoint)54.6 ± 25.060.7 ± 31.50.18
Recurrent moderate/severe MR32.6%2.3%<0.001
 Moderate28.4%2.3%
 Severe4.2%0%
Death14.3%17.6%0.45
MV reoperation2.4%0%0.25
Major adverse cardiac events32.5%33.6%0.86
New York Heart Association functional class III/IV9.0%14.0%0.28
Minnesota Living With Heart Failure score24.5 ± 23.119.6 ± 19.40.12

Adapted with permission from Acker et al. (60).

Values are mean ± SD or %.

LVESVI = left ventricular end-systolic volume index; MV = mitral valve.

  • Adjusted for death.

  • Death, stroke, New York Heart Association functional class increase by ≥1 grade, heart failure rehospitalization, or mitral valve reoperation.