Table 1

Study Outcomes at the 5-Year Follow-Up

EndpointPCI
(n = 300)
CABG
(n = 300)
Hazard Ratio
(95% CI)
p Value
MACCE52 (17.5)42 (14.3)1.27 (0.84–1.90)0.26
 Death from any cause17 (5.7)23 (7.9)0.73 (0.39–1.37)0.32
 Cardiac11 (3.8)20 (6.9)0.54 (0.26–1.13)0.098
 Noncardiac6 (2.0)3 (1.1)1.98 (0.49–7.91)0.33
Myocardial infarction6 (2.0)5 (1.7)1.20 (0.37–3.93)0.76
 Q-wave MI4 (1.4)3 (1.0)1.33 (0.30–5.95)0.71
 Non–Q-wave MI2 (0.7)2 (0.7)0.99 (0.14–7.06)1.00
Stroke2 (0.7)2 (0.7)0.99 (0.14–7.02)0.99
Death, MI, or stroke25 (8.4)28 (9.6)0.89 (0.52–1.52)0.66
Repeat revascularization38 (13.0)21 (7.3)1.86 (1.09–3.17)0.020
 TVR36 (12.4)18 (6.3)2.05 (1.17–3.62)0.011
 Ischemia driven33 (11.4)16 (5.5)2.11 (1.16–3.84)0.012
 Clinically driven27 (9.3)15 (5.2)1.83 (0.97–3.44)0.057
Death, MI, or ischemia-driven TVR50 (16.8)40 (13.7)1.28 (0.85–1.94)0.24

Values are n (%) unless otherwise indicated.

CABG = coronary artery bypass grafting; CI = confidence interval; MACCE = major adverse cardiac or cerebrovascular event(s); MI = myocardial infarction; PCI = percutaneous coronary intervention; TVR = target vessel revascularization.

  • Percentages are Kaplan-Meier estimates from the intention-to-treat analysis. A log-rank test was used to calculate p values. Ischemia-driven TVR was defined as any repeat revascularization with either PCI or CABG in the treated vessel having at least 50% diameter stenosis in the presence of ischemic signs or symptoms or at least 70% diameter stenosis in the absence of ischemic signs or symptoms. Clinically driven TVR excluded lesions without ischemic symptoms or signs from the ischemia-driven TVR.