Table 2

MOGE(S) Classification

Attribute Present
(Rate of LVRR)
Attribute Not Present
(Rate of LVRR)
p Value
(M)orphofunctional
 DCM35 (70/198)
(O)rgan involvement30 (9/30)36 (61/168)0.38
 Skeletal muscle29 (2/7)36 (68/191)0.70
 Auditory system60 (3/5)35 (67/193)0.35
 Kidney25 (1/4)36 (69/194)1.00
 Nervous system50 (1/2)35 (69/196)1.00
 Liver0 (0/2)36 (70/196)0.54
 Gastrointestinal system50 (1/2)35 (69/196)0.54
 Cutaneous40 (2/5)35 (68/193)1.00
 Ocular system40 (2/5)35 (68/193)1.00
 Mental retardation0 (0/1)36 (70/197)1.00
(G)enetic or familial25 (15/61)40 (55/137)0.04
 pathogenic mutation13 (2/16)37 (68/182)0.05
(E)tiology (nongenetic)36 (43/120)35 (27/78)0.86
 Idiopathic41 (22/54)33 (48/144)0.33
 Viral infection38 (14/37)35 (56/161)0.73
 Vir+ Infl−35 (8/23)35 (62/175)0.95
 Vir+ Infl+43 (6/14)35 (64/184)0.57
 Immune-mediated35 (27/78)36 (43/120)0.86
 Vir− Infl+38 (26/69)34 (44/129)0.62
 Vir− Infl− Syst+11 (1/9)37 (69/189)0.16
 Rhythm disturbances24 (4/17)37 (66/181)0.43
 Toxic exposure75 (9/12)33 (61/186)0.003
(S)tage of heart failure
 NYHA functional class ≥III42 (31/74)32 (39/124)0.14
Number of possible etiologies0.70
 041 (22/54)35 (68/190)0.72
 133 (30/92)
 239 (17/44)
 ≥325 (2/8)

Values are % (n/N).

LVRR = left ventricular reverse remodeling; Vir+ Infl− = virus-positive inflammatory-negative DCM; Vir− Infl+ = virus-negative inflammatory DCM; Vir+ Infl+ = virus-positive inflammatory DCM; Vir− Infl− Syst+ = virus-negative, inflammatory-negative DCM with proven systemic disease; other abbreviations as in Table 1.

  • Patients (n = 198) with echocardiographic follow-up showing the rates of LVRR after 12 months as a function of each attribute.

  • Includes genetic and nongenetic etiologies.

  • Overall p value.