Table 3

Association Between NIT Type and Positive Test Results

Positive Test Rate,
No. of Positive Test Results/Sample Size (%)
CTA Versus Stress Test
CTA Versus Stress Test
CTAStress TestOR (95% CI)p ValueOR (95% CI)p Value
Interaction between randomized arm and sex<0.001<.001
 CTA versus stress test in women184/2,332 (7.89)274/2,388 (11.47)0.66 (0.54–0.80)<0.0010.67 (0.55–0.82)<0.001
 CTA versus stress test in men350/2,168 (16.14)290/2,078 (13.96)1.19 (1.00–1.41)0.0471.23 (1.04–1.47)0.019

CI = confidence interval; NIT = noninvasive test; OR = odds ratio; other abbreviations as in Table 1.

  • Unadjusted models contained sex, randomized testing arm, and interaction term.

  • Adjusted for age, race, BMI, CAD equivalent, Framingham risk score, ASCVD score, 2011 Diamond and Forrester score, hypertension, dyslipidemia, diabetes, family history of premature CAD, sedentary lifestyle, smoking, typicality of chest pain, and physician’s estimation of likelihood of significant CAD.