Table 1

Baseline Characteristics

WomenMen
All Women
(n = 4,720)
CTA
(n = 2,332)
Stress Test
(n = 2,388)
p ValueAll Men
(n = 4,246)
CTA
(n = 2,168)
Stress Test
(n = 2,078)
p Value
Demographics
 Age, yrs62.4 ± 7.862.2 ± 7.762.6 ± 7.90.0758.9 ± 8.358.6 ± 8.259.2 ± 8.40.008
 Age ≥65 yrs1,627 (34.5)780 (33.4)847 (35.5)0.14961 (22.6)471 (21.7)490 (23.6)0.15
 Racial or ethnic minority1,052 (22.4)547 (23.6)505 (21.3)0.06913 (21.6)471 (21.9)442 (21.4)0.70
Cardiac risk factors
 Hypertension3,137 (66.5)1,534 (65.8)1,603 (67.1)0.332,673 (63.0)1,359 (62.7)1,314 (63.2)0.71
 Diabetes1,025 (21.7)500 (21.4)525 (22.0)0.65883 (20.8)436 (20.1)447 (21.5)0.26
 Metabolic syndrome1,761 (37.3)857 (36.7)904 (37.9)0.431,626 (38.3)816 (37.6)810 (39.0)0.37
 Dyslipidemia3,258 (69.0)1,621 (69.5)1,637 (68.6)0.482,812 (66.2)1,408 (64.9)1,404 (67.6)0.07
 Cerebrovascular disease220 (4.7)103 (4.4)117 (4.9)0.43140 (3.3)71 (3.3)69 (3.3)0.93
 Peripheral artery disease86 (1.8)42 (1.8)44 (1.8)0.9275 (1.8)32 (1.5)43 (2.1)0.14
 History of heart failure186 (3.9)90 (3.9)96 (4.0)0.77150 (3.5)73 (3.4)77 (3.7)0.55
 Current or former smoker2,162 (45.8)1,068 (45.8)1,094 (45.8)0.702,420 (57.0)1,224 (56.5)1,196 (57.6)0.02
 Family history of premature CAD1,602 (34.1)815 (35.1)787 (33.1)0.151,237 (29.2)645 (29.9)592 (28.6)0.35
 History of depression1,226 (26.0)599 (25.7)627 (26.3)0.65625 (14.7)286 (13.2)339 (16.3)0.004
 Participate in physical activity2,215 (47.0)1,101 (47.3)1,114 (46.7)0.702,393 (56.5)1,211 (56.0)1,182 (57.0)0.51
 BMI, kg/m230.4 ± 6.530.4 ± 6.430.4 ± 6.60.9330.5 ± 5.430.4 ± 5.430.5 ± 5.40.36
Cardiac risk scores
 Framingham15.0 ± 9.914.7 ± 9.515.3 ± 10.20.1728.7 ± 16.328.2 ± 16.229.2 ± 16.30.02
 ASCVD Pooled Cohort Equation12.5 ± 11.412.1 ± 10.912.9 ± 11.80.0616.9 ± 11.516.5 ± 11.417.3 ± 11.50.01
 Diamond and Forrester (2011)28.4 ± 12.328.1 ± 12.128.6 ± 12.50.2960.3 ± 17.560.0 ± 17.760.5 ± 17.20.13
Presenting symptoms
 Chest pain3,455 (73.2)1,744 (74.8)1,711 (71.7)0.023,067 (72.3)1,578 (72.9)1,489 (71.7)0.40
 Aching/dull808 (23.4)418 (24.0)390 (22.8)0.42847 (27.6)424 (26.9)423 (28.4)0.34
 Crushing/pressure/squeezing/ tightness1,832 (53.0)921 (52.8)911 (53.2)0.801,413 (46.1)754 (47.8)659 (44.3)0.05
 Provider characterization of chest pain0.880.72
 Typical526 (11.1)261 (11.2)265 (11.1)501 (11.8)260 (12.0)241 (11.6)
 Atypical3,671 (77.8)1,818 (78.0)1,853 (77.6)3,317 (78.1)1,683 (77.6)1,634 (78.6)
Physical examination
 Systolic BP, mm Hg131.0 ± 17.1130.8 ± 16.8131.1 ± 17.40.76131.6 ± 15.9131.4 ± 16.1131.8 ± 15.80.32
 Diastolic BP, mm Hg77.6 ± 10.277.4 ± 10.177.7 ± 10.30.2180.1 ± 10.280.2 ± 10.280.1 ± 10.20.83

Values are mean ± SD or n (%).

ASCVD = atherosclerotic cardiovascular disease; BMI = body mass index; BP = blood pressure; CAD = coronary artery disease; CTA = computed tomography angiography.