Table 1

Prevalence of Subclinical Coronary Atherosclerotic Plaque Ruptures (Percent) in Patients With Stable Coronary Heart Disease or Healthy Controls and in Patients With Acute Coronary Syndromes

First Author (Ref. #)Mode of AssessmentNumber of Stable CHD Patients or ControlsNonculprit Plaque Ruptures (%)Number of ACS PatientsNonculprit Plaque Ruptures (%)
Arbustini et al. (30)Pathology771710658
Cheruvu et al. (38)Pathology13313345
Rioufol et al. (41)IVUS2479
Kotani et al. (37)IVUS4863811
Schoenhagen et al. (36)IVUS92410519
Hong et al. (35)IVUS113512217
Tanaka et al. (29)IVUS4524
Takano et al. (34)Angioscopy3279
Tanaka et al. (33)OCT4524
Tian et al. (22)OCT8210
Shimamura et al. (32)OCT19117

Multiple asymptomatic plaque ruptures are more frequently found in patients with ACS than in those with stable CHD or healthy controls, indicating the systemic inflammatory state in the coronary arteries with acute events.

ACS = acute coronary syndrome; CHD = coronary heart disease; IVUS = intravascular ultrasound; OCT = optical coherence tomography.

  • Healthy controls.