Table 2

Absolute Risks and Negative Predictive Values for Myocardial Infarction or Death at 30, 180, and 365 Days After Discharge From the ED

CharacteristicsHigh-Sensitivity Cardiac Troponin T Level (ng/l)
<5 (n = 8,883)5–14 (n = 3,150)>14 (n = 2,579)
Proportion admitted1,917 (21)1,397 (44)2,104 (82)
Myocardial infarction
30 days
 No. of events1597676
 Absolute risk0.17 (0.09–0.27)3.08 (2.48–3.68)26.2 (24.5–27.9)
 Negative predictive value99.8 (99.7–99.9)96.9 (96.3–97.5)73.8 (72.1–75.5)
180 days
 No. of events33115724
 Absolute risk0.37 (0.24–0.54)3.65 (2.99–4.30)28.1 (26.3–29.8)
 Negative predictive value99.6 (99.4–99.7)96.4 (95.7–97.0)71.9 (70.2–73.7)
365 days
 No. of events54134753
 Absolute risk0.61 (0.45–0.78)4.25 (3.55–4.96)29.2 (27.4–31.0)
 Negative predictive value99.4 (99.2–99.5)95.7 (95.0–96.5)70.8 (69.0–72.6)
Death
 30 days
 No. of events21366
 Absolute risk0.023 (0.001–0.054)0.41 (0.19–0.64)2.56 (1.95–3.17)
 Negative predictive value100.0 (99.9–100.0)99.6 (99.4–99.8)97.4 (96.8–98.1)
180 days
 No. of events1566216
 Absolute risk0.17 (0.083–0.25)2.09 (1.59–2.59)8.38 (7.31–9.44)
 Negative predictive value99.8 (99.7–99.9)97.9 (97.4–98.4)91.6 (90.6–92.7)
365 days
 No. of events38108342
 Absolute risk0.43 (0.29–0.56)3.43 (2.79–4.06)13.3 (12.0–14.6)
 Negative predictive value99.6 (99.4–99.7)96.6 (95.9–97.2)86.7 (85.4–88.0)
  • According to the first high-sensitivity cardiac troponin T level, in 14,612† patients who sought medical attention for chest pain at Karolinska University Hospital from December 2010 to December 2012.

  • Twenty-four patients with a first high-sensitivity cardiac troponin T level of <5 ng/l were excluded because they had electrocardiographic changes suggestive of myocardial infarction at the time of presentation to the emergency department. Absolute risks and negative predictive values are given as percentage (95% confidence interval).