TableĀ 21

Recommendations for Treatment of HFpEF

RecommendationsCORLOE
Systolic and diastolic blood pressure should be controlled according to published clinical practice guidelinesIB (27,91)
Diuretics should be used for relief of symptoms due to volume overload.IC
Coronary revascularization for patients with CAD in whom angina or demonstrable myocardial ischemia is present despite GDMTIIaC
Management of AF according to published clinical practice guidelines for HFpEF to improve symptomatic HFIIaC
Use of beta-blocking agents, ACE inhibitors, and ARBs for hypertension in HFpEFIIaC
ARBs might be considered to decrease hospitalizations in HFpEFIIbB (589)
Nutritional supplementation is not recommended in HFpEFIII: No BenefitC

ACEĀ indicates angiotensin-converting enzyme; AF, atrial fibrillation; ARBs, angiotensin-receptor blockers; CAD, coronary artery disease; COR, Class of Recommendation; GDMT, guideline-directed medical therapy; HF, heart failure; HFpEF, heart failure with preserved ejection fraction; LOE, and Level of Evidence.