Table 2

CMR and TTE Results

HFpEF
(n = 24)
Control
(n = 12)
p Value
LVEDV, ml140 ± 38139 ± 310.98
LVEDV index, ml/m271.6 ± 14.069.5 ± 13.70.68
LVESV, ml56 ± 2158 ± 210.66
LVESV index, ml/m228.4 ± 9.428.9 ± 9.60.88
LVEF, %60.2 ± 7.258.5 ± 7.60.76
LV mass, g185 (156–240)170 (146–189)0.13
LV mass index, g/m299 (85–128)82 (72–100)0.04
Myocardial T1 pre-contrast, ms1,074 (1,044–1,107)1,061 (1,000–1,097)0.21
Blood T1 pre-contrast, ms1,607 (1,576–1,652)1,526 (1,477–1,599)<0.01
Myocardial T1 post-contrast, ms453 (418–498)488 (456–503)0.08
Blood T1 post-contrast, ms344 (309–373)356 (325–378)0.30
Focal LGE present4 (17)0 (0)0.12
Extracellular volume fraction, %32.9 ± 3.228.9 ± 3.0<0.01
LAESVi, ml/m239.9 ± 14.522.6 ± 6.3<0.01
E velocity max, m/s0.89 ± 0.20.66 ± 0.1<0.01
A velocity max, m/s0.80 ± 0.20.68 ± 0.20.12
E/A ratio1.0 (0.8–1.6)0.9 (0.8–1.3)0.46
E′ septal, m/s0.06 ± 0.020.09 ± 0.02<0.01
E′ lateral, m/s0.07 ± 0.020.12 ± 0.03<0.01
E/E′ septal ratio16.4 ± 4.87.9 ± 1.1<0.01
E/E′ lateral ratio13.4 ± 4.95.9 ± 1.2<0.01
E/E′ mean ratio14.8 ± 4.16.9 ± 0.9<0.01
E deceleration time, ms200 ± 51206 ± 400.76
Ar-A duration, ms38 (26–42)4 (0–23)<0.01

Values are mean ± SD, median (interquartile range), or n (%).

Ar = pulmonary venous flow reversal; CMR = cardiac magnetic resonance; EDV = end-diastolic volume; EF = ejection fraction; ESV = end-systolic volume; HFpEF = heart failure with preserved ejection fraction; LAESVi = left atrial end-systolic volume index; LV = left ventricular; LGE = late gadolinium enhancement; LVEF = left ventricular ejection fraction; LVEDV = left ventricular end diastolic volume; LVESV = left ventricular end systolic volume; TTE = transthoracic echocardiography.