Table 2

Factors Associated With Ischemic Stroke in Intermittent Versus Sustained AF: Age-adjusted Relative Riskslegend

Intermittent AFSustained AF
nAge-adjusted RRp ValuenAge-adjusted RRp Value
Age per decade (yrs)2.2< 0.0012.1< 0.001
Women1681.3n.s.3982.0< 0.001
Hypertension2243.60.0028322.3< 0.001
Diabetes mellitus601.7n.s.2441.70.04
Alcohol use (≥14 per week)27n.s.1450.40.03
Systolic blood pressure >160 torr531.6n.s.1394.0< 0.001
Hormone use (n = 1,182)412.2n.s.573.30.007
Carotid surgery or bruit202.8n.s.771.4n.s.
Prior stroke or TIA314.50.0071283.2< 0.001
Peripheral arterial disease188.50.0021141.3n.s.
  • During aspirin therapy. Left atrial diameter by M-mode echocardiography averaged 4.3 cm among participants with intermittent AF with and without stroke.

  • No strokes occurred in these 27 patients. The age-adjusted RR approaches zero, but no estimate for the upper bound of the 95% confidence interval is available for the model.

  • legend AF = atrial fibrillation; n.s. = not significant (p ≥ 0.05); RR = relative risk; TIA = transient ischemic attack.