Intermittent AF | Sustained AF | |||||
---|---|---|---|---|---|---|

n | Age-adjusted RR | p Value | n | Age-adjusted RR | p Value | |

Age per decade (yrs) | — | 2.2 | < 0.001 | — | 2.1 | < 0.001 |

Women | 168 | 1.3 | n.s. | 398 | 2.0 | < 0.001 |

Hypertension | 224 | 3.6 | 0.002 | 832 | 2.3 | < 0.001 |

Diabetes mellitus | 60 | 1.7 | n.s. | 244 | 1.7 | 0.04 |

Alcohol use (≥14 per week) | 27 | † | n.s. | 145 | 0.4 | 0.03 |

Systolic blood pressure >160 torr | 53 | 1.6 | n.s. | 139 | 4.0 | < 0.001 |

Hormone use (n = 1,182) | 41 | 2.2 | n.s. | 57 | 3.3 | 0.007 |

Carotid surgery or bruit | 20 | 2.8 | n.s. | 77 | 1.4 | n.s. |

Prior stroke or TIA | 31 | 4.5 | 0.007 | 128 | 3.2 | < 0.001 |

Peripheral arterial disease | 18 | 8.5 | 0.002 | 114 | 1.3 | n.s. |

↵∗ During aspirin therapy. Left atrial diameter by M-mode echocardiography averaged 4.3 cm among participants with intermittent AF with and without stroke.

↵† No strokes occurred in these 27 patients. The age-adjusted RR approaches zero, but no estimate for the upper bound of the 95% confidence interval is available for the model.

↵legend AF = atrial fibrillation; n.s. = not significant (p ≥ 0.05); RR = relative risk; TIA = transient ischemic attack.