Table 3

Referral to Coronary Angiographylegend

VariableUnivariate AnalysisMultivariate Analysis
Chi-Squarep ValueOR (95% CI)Chi-Squarep ValueOR (95% CI)
SSS(5-point decrease)2,066< 0.0012.4 (2.3–2.5)147<0.0011.5 (1.4–1.6)
SRS(1-point increase)2,020< 0.0011.3 (1.29–1.32)273<0.0011.18 (1.17–1.20)
Cardiac enlargement502< 0.0013.9 (3.3–4.3)
Gender (male)202< 0.0012.2 (2.0–2.5)16<0.0011.3 (1.1–1.5)
Chest pain class62< 0.0011.2 (1.1–1.2)
Diabetes56< 0.0011.3 (1.2–1.4)
Smoking23< 0.0011.2 (1.1–1.3)40.0471.1 (1.0–1.2)
Symptom status22< 0.0011.3 (1.2–1.5)17<0.0011.3 (1.2–1.5)
Pharmacologic stress14< 0.0011.2 (1.1–1.4)90.0031.2 (1.1–1.4)
Age (10-year increase)100.0021.07 (1.03–1.11)27<0.0010.87 (0.82–0.91)
Hypertension90.0041.2 (1.1–1.3)
Hyperlipidemia50.0341.1 (1.0–1.2)
  • Variables without numbers in the multivariate analysis did not meet the entry criteria into the final model;

  • a summed stress score (SSS) of 56 represents a normal image;

  • a summed reversibility score (SRS) of 0 represents a nonischemic image. Final model: chi-square = 3,051, p < 0.001, C-index = 0.87. Bootstrapping analysis SSS and SRS came into every model, symptom status in >99% of the models, gender in 97%, pharmacologic stress in 81% and age in 79%.

  • legend CI = confidence interval; OR = odds ratio.