Table 4

Intravascular Ultrasonographic Measures of Atheroma Burden in Patients With Normal, Pre-Hypertensive, and Hypertensive Average Blood Pressure Levels During the Study

Normal (n = 76)Pre-Hypertensive (n = 155)Hypertensive (n = 41)p Value
Baseline atheroma volume (mm3)
 Mean ± SD187.9 ± 79.5190.8 ± 81.6202.2 ± 61.70.29
 Median (interquartile range)180.8 (133.1–238.1)171.7 (137.4–241.2)205.4 (158.7–250.9)
Follow-up atheroma volume (mm3)
 Mean ± SD184.5 ± 74.6191.7 ± 82.0211.5 ± 64.70.001
 Median (interquartile range)168.2 (129.3–238.4)179.5 (133.1–227.3)212.2 (155.2–259.9)
 p value(compared to baseline)0.080.610.001
Change in atheroma volume (mm3)
 Least-square mean ± SE−4.6 ± 2.60.9 ± 1.812.0 ± 3.6<0.001

 Abbreviations as in Tables 1 and 2.

  • Kruskal-Wallis test;

  • analysis of covariance model with rank-transformed baseline values, LDL/HDL cholesterol ratio and triglycerides as covariates;

  • analysis of covariance model with rank-transformed LDL/HDL cholesterol ratio and triglycerides as covariates. Since 2 patients had incomplete plasma lipid data, the results of a total of 272 patients are shown.