Table 3

CW Doppler Flow and TDI Parameters in Patients With OHCM, Patients With NOHCM, and Control Subjects

ModalityVariableOHCMNOHCMControlp Value
CW DopplerRR (ms)862 ± 176934 ± 191966 ± 172NS
Vmax (m/s)5.5 ± 1.11.5 ± 0.41.2 ± 0.2<0.001
PEP (ms)89 ± 18104 ± 23107 ± 160.003
Q to Vmax (ms)268 ± 53199 ± 36188 ± 37<0.001
ETime (ms)330 ± 43298 ± 44299 ± 370.016
Q to Vmax/ETime0.54 ± 0.080.32 ± 0.080.27 ± 0.09<0.001
Septal TDISeptal Vs (cm/s)9.5 ± 3.19.6 ± 1.710.9 ± 2.4NS
Septal VTI (cm)1.2 ± 0.61.9 ± 0.42.0 ± 0.4<0.001
Septal PreCTime (ms)105 ± 37108 ± 28104 ± 13NS
Septal Q to Vs (ms)161 ± 45178 ± 38159 ± 26NS
Septal CTime (ms)203 ± 68271 ± 41273 ± 40<0.001
Septal CTime/ETime0.63 ± 0.190.91 ± 0.140.91 ± 0.12<0.001
Septal deceleration (cm/s2)78 ± 3548 ± 2152 ± 15<0.001
Lateral wall TDILateral Vs (cm/s)11.5 ± 3.311.1 ± 2.111.3 ± 2.1NS
Lateral VTI (cm)1.7 ± 0.52.3 ± 0.41.8 ± 0.40.003
Lateral PreCTime (ms)135 ± 47106 ± 26116 ± 210.037
Lateral Q to Vs (ms)196 ± 65185 ± 59177 ± 38NS
Lateral CTime (ms)238 ± 45297 ± 64258 ± 350.002
Lateral CTime/ETime0.73 ± 0.141.0 ± 0.230.87 ± 0.14<0.001
Lateral deceleration (cm/s2)81 ± 3552 ± 2459 ± 22<0.001

CTime = duration of contraction; PreCTime = time to onset of contraction; Q to Vmax = time to peak ejection velocity; Q to Vs = time to peak contraction velocity; TDI = tissue Doppler imaging; Vmax = peak flow velocity; Vs = peak systolic tissue velocity; VTI = velocity time integral of systolic tissue velocity; other abbreviations as in Tables 1 and 2.

  • OHCM versus Control;

  • NOHCM versus others.