Table 1

Clinical Characteristics of Study Subjects and Those Excluded Due to Missing Childhood Apolipoprotein Data

Study SubjectsExcludedp Value
n8791,386
Male subjects (%)45.744.40.56
Baseline characteristics in 1980
 Age (yrs)10.9 ± 5.010.5 ± 5.00.08
 LDL cholesterol (mmol/l)3.39 ± 0.783.48 ± 0.820.01
 HDL cholesterol (mmol/l)1.56 ± 0.311.56 ± 0.310.91
 Triglycerides (mmol/l)0.66 ± 0.310.67 ± 0.310.54
 Systolic blood pressure (mm Hg)112 ± 12113 ± 120.19
 BMI (kg/m2)17.9 ± 3.117.9 ± 3.10.90
 Insulin (mU/l)9.8 ± 6.09.7 ± 5.90.39
 CRP (mg/l)0.9 ± 2.71.1 ± 3.20.80
 Smoking (%)28.024.60.19
 ApoA-I (g/l)1.52 ± 0.25
 ApoB (g/l)0.93 ± 0.21
Characteristics in 2001
 Age (yrs)31.9 ± 5.031.5 ± 5.00.08
 LDL cholesterol (mmol/l)3.27 ± 0.823.28 ± 0.860.64
 HDL cholesterol (mmol/l)1.29 ± 0.321.29 ± 0.320.83
 Triglycerides (mmol/l)1.32 ± 0.861.35 ± 0.850.54
 Systolic blood pressure (mm Hg)117 ± 13116 ± 130.19
 BMI (kg/m2)25.1 ± 4.625.0 ± 4.30.58
 Smoking (%)26.928.70.36
 ApoA-I (g/l)1.51 ± 0.251.49 ± 0.260.17
 ApoB (g/l)1.07 ± 0.251.06 ± 0.270.37
 Carotid IMT (mm)0.58 ± 0.090.58 ± 0.090.50
 Brachial FMD (%)8.12 ± 4.437.92 ± 4.420.30

Apo = apolipoprotein; BMI = body mass index; CRP = C-reactive protein; FMD = flow-mediated dilatation; HDL = high-density lipoprotein; IMT = intima-media thickness; LDL = low-density lipoprotein.

  • Among subjects ages 12 to 18 years.