Table 4

Bivariate Relations Between Childhood/Adolescent Apolipoproteins and Lipids on Adulthood Brachial FMD Measured 21 Years Later

Brachial FMD
Age 3–9 Yrs (n = 375)Age 12–18 Yrs (n = 438)All (n = 813)
β (95% CI)p Valueβ (95% CI)p Valueβ (95% CI)p Value
ApoA-I0.48 (0.02 to 0.94)0.040.43 (0.01 to 0.85)0.040.45 (0.13 to 0.77)0.004
HDL cholesterol0.03 (−0.43 to 0.49)0.910.17 (−0.25 to 0.59)0.430.10 (−0.22 to 0.42)0.51
ApoB−0.36 (−0.82 to 0.10)0.12−0.34 (−0.76 to 0.08)0.11−0.35 (−0.67 to −0.03)0.03
LDL cholesterol−0.09 (−0.55 to 0.37)0.70−0.15 (−0.57 to 0.27)0.49−0.13 (−0.45 to 0.19)0.44
Non-HDL cholesterol−0.05 (−0.51 to 0.41)0.84−0.11 (−0.53 to 0.31)0.62−0.08 (−0.40 to 0.24)0.61
ApoB/apoA1 ratio−0.56 (−1.02 to −0.10)0.01−0.55 (−0.99 to −0.11)0.01−0.56 (−0.88 to −0.24)<0.001
LDL/HDL ratio−0.09 (−0.55 to 0.37)0.70−0.16 (−0.58 to 0.26)0.45−0.13 (−0.45 to 0.19)0.41
Non-HDL/HDL ratio−0.04 (−0.50 to 0.42)0.85−0.12 (−0.56 to 0.32)0.58−0.09 (−0.41 to 0.23)0.59

Beta values are regression coefficients (expressed in percents) for a 1-SD change (specific for age and gender) in continuous variables. p values are from regression analysis testing for linear relationship between risk factors and FMD.

Abbreviations as in Tables 1 and 2.