Table 3

Baseline Laboratory Measurements in Treatment Groups

Clopidogrel 300 mg (n = 30)Clopidogrel 600 mg (n = 30)Clopidogrel Alone (n = 60)Clopidogrel + Eptifibatide (n = 60)Clopidogrel 300 mg + Eptifibatide (n = 30)Clopidogrel 600 mg + Eptifibatide (n = 30)
LTA, 5 μM ADP (%)60 ± 962 ± 1661 ± 1261 ± 960 ± 1061 ± 9
LTA, 20 μM ADP (%)75 ± 777 ± 976 ± 975 ± 1274 ± 1576 ± 8
GP IIb/IIIa receptor, MFI (stimulated)138 ± 35141 ± 11140 ± 26126 ± 14121 ± 8128 ± 17
P-selectin, % positive cells (stimulated)42 ± 2241 ± 2141 ± 2037 ± 1236 ± 1039 ± 14
TNF-α (pg/ml)78 ± 1393 ± 1487 ± 2284 ± 1585 ± 1583 ± 11
CRP (mg/l)3.7 ± 1.43.3 ± 1.53.5 ± 1.53.6 ± 1.53.8 ± 1.33.2 ± 1.4

ADP = adenosine diphosphate; CRP = C-reactive protein; GP = glycoprotein; LTA = light transmittance aggregometry; MFI = mean fluorescence intensity; TNF = tumor necrosis factor.

  • p < 0.01 clopidogrel alone versus clopidogrel + eptifibatide.