Table 3

Baseline and Follow-Up Carotid Measures

Standard Group (n = 204)Aggressive Group (n = 223)Bonferroni Adjusted
Mean (95% CI)Ezetimibe Group (E+) Mean (95% CI)No Ezetimibe Group (E−) Mean (95% CI)F Test (p Value)Group Difference (p Value) E+ vs. E−Group Difference (p Value) E+ vs. SGroup Difference (p Value) E− vs. S
CIMT, mm
 Baseline0.794 (0.77 to 0.82)0.819 (0.77 to 0.86)0.813 (0.78 to 0.84)0.46
 18 months0.803 (0.78 to 0.82)0.815 (0.78 to 0.86)0.810 (0.78 to 0.84)0.84
 36 months0.833 (0.81 to 0.86)0.794 (0.75 to 0.84)0.801 (0.77 to 0.83)0.17
 Mean change, 18 months0.009 (−0.01 to 0.03)−0.006 (−0.03 to 0.02)−0.005 (0.02 to 0.014)0.48
 Mean change, 36 months0.039 (0.02 to 0.06)−0.025 (−0.05 to 0.003)−0.012 (0.03 to 0.008)0.00010.01 (0.999)0.06 (0.001)0.05 (0.001)
Plaque score
 Baseline1.83 (1.6 to 2.1)1.93 (1.5 to 2.3)1.88 (1.6 to 2.1)0.89
 18 months2.02 (1.8 to 2.2)2.10 (1.7 to 2.5)2.11 (1.9 to 2.4)0.84
 36 months2.33 (2.1 to 2.6)2.35 (1.9 to 2.8)2.49 (2.2 to 2.8)0.65
 Mean change, 18 months0.18 (0.04 to 0.3)0.17 (−0.04 to 0.4)0.21 (0.06 to 0.4)0.94
 Mean change, 36 months0.51 (0.4 to 0.7)0.42 (0.1 to 0.7)0.61 (0.4 to 0.8)0.50

CIMT = carotid artery intima-media thickness; other abbreviations as in Table 1.