Table 1

Baseline Characteristics of Patients Who Completed First MRI Scan

NAPlacebo
Men31 (94%)32 (94%)
Age (yrs)65 ± 965 ± 9
Diabetes mellitus21 (64%)22 (65%)
Hypertension28 (85%)24 (71%)
History of smoking30 (91%)26 (76%)
Peripheral vascular disease14 (42%)10 (29%)
Previous myocardial infarction17 (53%)15 (44%)
Previous stroke3 (9%)6 (18%)
Previous coronary angioplasty15 (45%)14 (41%)
Previous coronary bypass grafting11 (33%)10 (29%)
Medications
 ACE inhibitor25 (76%)24 (71%)
 Beta-blocker22 (67%)21 (62%)
 Aspirin31 (94%)30 (88%)
 Clopidogrel14 (42%)9 (26%)
 Statin (mean dose, mg)33 (100%)34 (100%)
  Simvastatin20 (35)24 (36)
  Atorvastatin12 (24)10 (23)
  Rosuvastatin1 (40)0 (0)
 Oral hypoglycemic agents16 (48%)15 (44%)
 Insulin11 (33%)6 (18%)
BMI (kg/m2)31 ± 530 ± 5
SBP (mm Hg)132 ± 15141 ± 22
DBP (mm Hg)75 ± 876 ± 10
Heart rate (beats/min)63 ± 1060 ± 10

ACE = angiotensin-converting enzyme; BMI = body mass index; DBP = diastolic blood pressure; MRI = magnetic resonance imaging; NA = nicotinic acid; SBP = systolic blood pressure.