Table 1

Multivariate Risk Factor Analysis for CHD Death or Nonfatal MIlegend

Risk FactorEvent Rate (%)Hazard Ratio95% CIp ValueRisk Points
Total cholesterol:0.003
 <5.5 mmol/l12.91.000
 ≥5.5 mmol/l14.71.201.06–1.351
HDL cholesterol:<0.001
 >1.0 mmol/l11.81.000
 ≤1.0 mmol/l15.21.301.14–1.472
Age:<0.001
 <60 yr11.21.000
 60–64 yr12.81.160.98–1.371
 65–69 yr15.91.481.27–1.732
 ≥70 yr19.61.891.60–2.233
Gender:0.006
 Female12.01.000
 Male14.31.271.07–1.502
Smoking status:<0.001
 Nonsmoker13.51.000
 Current smoker17.51.431.19–1.713
Nature of prior ACS:<0.001
 Unstable angina11.31.000
 Single MI13.31.301.12–1.501
 Multiple MIs25.12.281.93–2.706
Revascularization:<0.001
 Never12.31.000
 Before ACS17.51.241.05–1.45
 Since ACS9.20.650.55–0.76subtract 4
History of stroke:0.032
 No13.61.000
 Yes21.81.361.02–1.643
Diabetes mellitus:<0.001
 No13.31.000
 Yes20.91.481.24–1.753
History of hypertension:0.035
 No12.91.000
 Yes15.31.141.01–1.281
Dyspnea grade:0.007
 NYHA <III13.21.00
 NYHA ≥III21.11.281.07–1.53
Angina grade:0.014
 CCVS <III13.21.00
 CCVS ≥III21.11.271.05–1.53
Angina duration:0.028
 ≤5 years13.21.00
 >5 years18.61.201.02–1.40
Region:0.004
 Australia13.01.00
 New Zealand15.71.191.06–1.34
Aspirin usage:0.007
 No17.71.00
 Yes13.40.820.71–0.95
  • The prognostic index is the product of the hazard ratios associated with the patient’s risk factor profile;

  • the risk score is the sum of the risk points associated with the patient’s risk factor profile. Risk factors without risk points were not considered for the simplified risk score;

  • to convert values to mg/dl, multiply by 38.67.

  • legend ACS = acute coronary syndrome; CCVS = Canadian Cardiovascular Society; CHD = coronary heart disease; CI = confidence interval; HDL = high-density lipoprotein; MI = myocardial infarction; NYHA = New York Heart Association.