Table 2

Summary of the Enzymatic and Genetic Screening of the Index Patients

CoruñaMurciaAlicanteTotal
Patients (n)200148160508
Male gender (%)64765565
Age (yrs)58 ± 1555 ± 1659 ± 1858 ± 16
Age ≥40 yrs (%)87838284
Plasma enzymatic activity (% of control)83 ± 26112 ± 47104 ± 2999 ± 37
Men with enzymatic activity ≤30, n (%)1 (0.7)3 (2.4)2 (2.3)6 (1.8)
Women with enzymatic activity ≤50, n (%)9 (12.5)009 (5)
Patients with low enzymatic activity, n (%)10 (5)3 (2)2 (1.3)15 (3)
Patients with GLApolymorphisms, n (%)3 (1.5)2 (1.4)05 (1)
Patients with GLAmutations, n (%)2 (1)1 (0.7)2 (1.3)5 (1)