Table 7

Agents for Acute Vasodilator Testing

EpoprostenolAdenosineNitric Oxide
Route of AdministrationIntravenous infusionIntravenous infusionInhaled
Dose Titration2 ng/kg/min every 10 to 15 min50 mcg/kg/min every 2 minNone
Dose Range2 to 10 ng/kg/min50 to 250 mcg/kg/min10 to 80 ppm
Side EffectsHeadache, nausea, lightheadednessDyspnea, chest pain, AV blockIncreased left heart filling pressure in susceptible patients

AV indicates atrioventricular.