Table 1

Randomized Controlled Trials

BASKET-AMI (32)DEDICATION-AMI (29)Di Lorenzo et al. (21)HAAMU- STENT (22)MISSION (30)MULTI-STRATEGY (28)PASSION (24)SELECTION (26)SESAMI (25)STRATEGY (27)TYPHOON (23)HORIZONS-AMI STENT (31)Diaz de la Llera et al. (33)
No. screened1,6872135751,0301,0374232,0193,602150
No. enrolled217626270164376745619803201757123,006120
Mean follow-up, months18812171281271224121212
Clopidogrel duration, months61261212369123669
Stent typeSES, PESSES, PESSES, PESPESSESSESPESPESSESSESSESPESSES
Timing, h<12<12<12*<12<12<12<12*<12<12<12
GP IIb/IIIa, %65%96%100%100%27%100%75%100%72%50%100%
Symptom to balloon, min200196180201240180230222174
No. of centers1211162111481231
Rescue PCI, %45%0%0%18%0%18%
LAD culprit, %41%44%55%43%50%50%50%45%46%43%43%
Age, yrs, mean626463596361606163596064
Female, %27%28%22%25%24%18%19%27%22%23%21%
Diabetes, %10%15%11%12%21%14%16%16%16%
Primary end pointDeath, MI, TVR and stroke≥70% ST-segment resolution 90 min after PCIDeath, MI, TVR, and strokeIn-segment late lossIn-segment late lossDeath, MI, TVRDeath, MI, TLRNeointimal hyperplasia by IVUSBinary restenosisDeath, MI, stroke, and binary restenosisTVFDeath, MI, stroke, and STDeath, MI, TLR

AMI = acute myocardial infarction; GP = glycoprotein; IVUS = intravascular ultrasound; LAD = left anterior descending artery; MI = myocardial infarction; PCI = percutaneous coronary intervention; PES = paclitaxel=eluting stent(s); SES = sacrolimus-eluting stent(s); ST = stent thrombosis; TLR = target lesion revascularization; TVF = target vessel failure.

  • * Up to 24 h was permitted with evidence of ongoing ischemia;

  • composite of target vessel revascularization (TVR), recurrent infarction, or target vessel-related death at 1 year.