Table 5

Comparison of CT Characteristics of 2- or 1-Feature Positive Plaques That Did or Did Not Develop ACS

2-Feature Positive Plaques1-Feature Positive Plaques
ACS (n = 11)No ACS (n = 63)p ValueACS 0–12 Months (n = 11)ACS 13–24 Months (n = 5)No ACS in 24 Months (n = 24)p Value
Remodeling index (%)0.0030.005
 Mean ± SE126.7 ± 3.9113.4 ± 1.6131.2 ± 5.1120.8 ± 5.9113.4 ± 1.6
 95% confidence interval(118.9 to 134.5)(110.2 to 116.6)(120.9 to 141.4)(109.1 to 132.6)(110.3 to 116.6)
Total plaque volume (mm3)<0.001<0.001
 Mean ± SE134.9 ± 14.157.8 ± 5.7166.5 ± 17.892.8 ± 20.458.1 ± 5.5
 95% confidence interval(106.8 to 162.9)(46.3 to 69.2)(131.1 to 201.9)(52.1 to 133.6)(47.1 to 69.1)
LAP volume (mm3)<0.001<0.001
 Mean ± SE20.4 ± 3.41.1 ± 1.430.5 ± 4.16.9 ± 4.81.2 ± 1.3
 95% confidence interval(13.58 to 27.21)(−1.7 to 3.9)(22.3 to 38.8)(−2.6 to 16.4)(−1.3 to 3.8)
Maximum LAP area (mm2)<0.001<0.001
 Mean ± SE3.2 ± 0.50.5 ± 0.24.7 ± 0.51.2 ± 0.60.5 ± 0.2
 95% confidence interval(2.3 to 4.1)(0.2 to 0.9)(3.6 to 5.7)(−6.6 to 2.4)(0.2 to 0.9)
Maximum LAP area/plaque area (%)0.001<0.001
 Mean ± SE21.4 ± 3.77.7 ± 1.531.5 ± 4.58.1 ± 5.27.8 ± 1.4
 95% confidence interval(14.1 to 28.7)(4.7 to 10.6)(22.5 to 40.4)(−2.2 to 18.4)(5.0 to 10.5)

Analysis of covariance adjusted for age, hypertension, hyperlipidemia, and prior MI. p values represent comparison across groups.

LAP = low-attenuation plaque; NCP = noncalcified plaque; other abbreviations as in Table 2.