Table 5

Clinical and Peri-Procedural Characteristics of the Patients, According to the Occurrence of Cumulative Late Mortality

Cumulative Late Mortality
VariablesYes (n = 75)No (n = 264)p Value
Baseline
 Age (yrs)82 ± 881 ± 80.748
 Male sex39 (52.0)113 (42.9)0.326
 BMI (kg/m2)25 ± 426 ± 50.389
 Diabetes21 (28.0)58 (22.0)0.226
 Dyslipidemia50 (66.7)191 (73.3)0.256
 Hypertension59 (78.7)193 (73.1)0.133
 Current smokers7 (9.3)13 (4.9)0.301
 Chronic atrial fibrillation/flutter33 (44.0)82 (31.1)0.044
 Coronary artery disease52 (69.3)182 (69.0)0.480
 Previous myocardial infarction46 (61.3)127 (48.1)0.190
 Previous PCI25 (33.3)74 (28.0)0.384
 Prior coronary artery bypass grafting19 (25.3)97 (36.7)0.076
 Cerebrovascular disease22 (29.3)55 (20.8)0.118
 Peripheral vascular disease30 (40.0)90 (34.1)0.164
 COPD30 (40.0)70 (26.5)0.039
 Creatinine (μmol/l)135 ± 79114 ± 840.103
 eGFR <60 ml/min52 (69.3)138 (52.3)0.004
 Dialysis3 (4.0)7 (2.7)0.653
 STS-PROM score (%)11.7 ± 8.19.3 ± 5.80.004
 Porcelain aorta10 (13.3)51 (19.3)0.198
 Frailty19 (25.3)66 (25.0)0.785
 Pulmonary hypertension29 (38.7)55 (20.8)0.002
 Severe mitral regurgitation8 (10.7)19 (7.2)0.447
 LVEF (%)55 ± 1556 ± 140.692
 LVEF <40%14 (18.7)40 (15.2)0.402
Peri-procedural variables
 Approach
  Transfemoral40 (53.3)122 (46.2)0.884
  Transapical35 (46.7)142 (53.8)
 Unsuccessful procedure*8 (10.7)10 (3.8)0.913
 Valve embolization2 (2.7)5 (1.9)0.244
 Need for a second valve2 (2.7)7 (2.7)0.756
 Conversion to open heart surgery3 (4.0)3 (1.1)0.003
 Need for hemodynamic support6 (8.0)8 (3.0)0.026
 Major access site complications15 (20.0)30 (11.4)0.035
 Life-threatening arrhythmias6 (8.0)22 (8.3)0.856
 Myocardial infarction2 (2.7)2 (0.8)0.035
 Stroke2 (2.7)6 (2.3)0.948
 Sepsis6 (8.0)4 (1.5)0.002
 Need for hemodialysis4 (5.3)5 (1.9)0.098
 Need for permanent pacemaker3 (4.0)14 (5.3)0.744

Values are expressed as n (%) or mean ± SD.

Abbreviations as in Table 1.

  • * Excluding procedural death.