Table 2

Platelet Activation Profiles According to HPPR Status

HPPRADPHPPRCOLLHPPRADP+COLL
YesNop ValueYesNop ValueYesNop Value
Antifibrinogen37 ± 2027 ± 19<0.00137 ± 2028 ± 200.00140 ± 1928 ± 20<0.001
PAC-149 ± 1934 ± 20<0.00144 ± 1936 ± 210.00448 ± 1936 ± 20<0.001
P-selectin44 ± 1831 ± 18<0.00137 ± 1933 ± 190.1943 ± 1933 ± 190.001

Values are mean ± SD. High post-treatment platelet reactivity to ADP- (HPPRADP), collagen- (HPPRCOLL), and both ADP- and collagen-induced (HPPRADP+COLL) aggregation. PAC-1 (PAC-1 FICT conjugated; Becton Dickinson, Rutherford, New Jersey).

ADP = adenosine disphosphate; COLL = collagen HPPR = high post-treatment platelet reactivity.