Table 3

Clinical and Peri-Procedural Characteristics of the Patients, According to the Occurrence of 30-Day Mortality

30-Day Mortality
VariablesYes (n = 36)No (n = 303)p Value
Baseline
 Age (yrs)81 ± 981 ± 80.836
 Male sex17 (47.2)135 (44.6)0.721
 BMI (kg/m2)25 ± 426 ± 50.399
 Diabetes6 (16.7)73 (24.1)0.407
 Dyslipidemia21 (58.3)220 (72.7)0.109
 Hypertension26 (72.2)226 (74.6)1.00
 Current smokers2 (5.6)18 (5.9)1.00
 Chronic atrial fibrillation/flutter13 (36.1)102 (33.7)0.709
 Coronary artery disease25 (69.4)209 (69.0)0.849
 Previous myocardial infarction23 (63.9)150 (49.5)0.077
 Previous PCI10 (27.8)89 (29.4)1.00
 Prior coronary artery bypass grafting10 (27.8)106 (34.9)0.460
 Cerebrovascular disease11 (30.6)66 (21.8)0.206
 Peripheral vascular disease13 (36.1)107 (35.3)0.854
 COPD12 (33.3)88 (29.1)0.559
 Creatinine (μmol/l)136 ± 89117 ± 820.201
 eGFR <60 ml/min27 (75.0)163 (53.8)0.020
 Dialysis1 (2.8)9 (2.9)1.00
 STS score (%)10.3 ± 6.39.8 ± 6.50.609
 Porcelain aorta7 (19.4)54 (17.8)0.819
 Frailty7 (19.4)78 (25.7)0.542
 Pulmonary hypertension14 (38.9)70 (23.1)0.039
 Severe mitral regurgitation6 (16.7)21 (7.0)0.049
 LVEF (%)55 ± 1555 ± 140.866
 LVEF <40%7 (19.4)47 (15.5)0.629
Procedural and 30-day outcome variables
 Approach
  Transfemoral16 (44.4)146 (48.2)0.726
  Transapical20 (55.6)157 (51.8)
 Unsuccessful procedure*2 (6.7)10 (3.3)0.295
 Valve embolization2 (5.6)5 (1.6)0.164
 Need for a second valve2 (5.6)7 (2.3)0.246
 Conversion to open heart surgery3 (8.3)3 (0.9)0.018
 Need for hemodynamic support5 (13.9)9 (2.9)0.010
 Major access site complications9 (25.0)36 (11.9)0.038
 Life-threatening arrhythmias5 (13.9)23 (7.6)0.199
 Myocardial infarction2 (5.6)2 (0.7)0.057
 Stroke2 (5.6)6 (1.9)0.204
 Sepsis3 (8.3)7 (2.3)0.078
 Need for hemodialysis1 (2.8)8 (2.6)1.00
 Need for permanent pacemaker1 (2.8)16 (5.3)1.00

Values are expressed as n (%) or mean ± SD.

Abbreviations as in Table 1.

  • * Excluding procedural death.