Table 2

Long-Term End Points

End PointInterventionControlRR (95% CI)p Value
Beginning of study up to 1 yr after completion
 Primary end point283 (37.2)323 (42.6)0.81 (0.69–0.96)0.013
 Heart failure174 (22.9)220 (29.0)0.73 (0.60–0.90)0.002
 Death189 (24.9)197 (25.9)0.94 (0.77–1.16)0.586
Beginning of trial up to 3 yrs after completion
 Primary end point423 (55.7)436 (57.5)0.88 (0.77–1.00)0.05
 Heart failure217 (28.5)266 (35.1)0.72 (0.60–0.87)0.0004
 Death326 (42.9)308 (40.6)1.02 (0.87–1.20)0.73

Values are n (%) unless otherwise noted.

CI = confidence interval; RR = relative risk