Table 1

Comparison Between Subclavian and Transfemoral TAVI

VariableTransfemoralSubclavianp Value
(n = 253)(n = 35)
Baseline characteristics
 Age (yrs)81.7 ± 6.480.6 ± 4.90.33
 Logistic EuroSCORE (%)19.1 ± 12.325.0 ± 14.70.02
 Coronary artery disease148 (58.5%)26 (74.2%)0.09
 Previous MI41 (16.2%)12 (34.3%)0.02
 Previous PCI61 (24.1%)12 (34.3%)0.22
 Carotid artery disease15 (5.9%)6 (17.1%)0.03
 Peripheral vascular disease54 (21.3%)26 (74.2%)<0.0001
 COPD47 (18.6%)14 (40.0%)0.007
 LVEF <50%94 (37.2%)23 (65.7%)0.004
Procedural results
 Procedural success246 (97.2%)35 (100%)1.00
 “Optimal” valve position153 (60.5%)31 (88.6%)0.001
 Major vascular complications25 (9.9%)1 (2.9%)0.34
 Blood transfusion47 (18.6%)13 (37.1%)0.02
30-day outcomes
 Mortality12 (4.7%)0 (0%)0.37
 Stroke11 (4.3%)1 (2.9%)0.86
 MACCE34 (13.4%)1 (2.9%)0.09

Data are expressed as mean ± SD or n (%).

COPD = chronic obstructive pulmonary disease; EuroSCORE = European System for Cardiac Operative Risk Evaluation; LVEF = left ventricular ejection fraction; MACCE = major adverse cardiovascular and cerebrovascular events; MI = myocardial infarction; PCI = percutaneous coronary intervention; TAVI = transcatheter aortic valve implantation.