Table 4

Comparisons of HR (95% CI) for the Relation of Blood Pressure Patterns in Early Adulthood With CHD Mortality: Our Results in Relation to Previously Published Studies

JNC-6 ClassificationHAHS (Unadjusted)University of Glasgow Alumni (12) (Unadjusted)HAHS (Adjusted*)Chicago Heart Association Study (11) (Adjusted)
No. of DeathsHR (95% Cl)No. of DeathsHR (95% Cl)No. of DeathsHR (95% Cl)No. of DeathsHR (95% Cl)
Optimal5731.00 (ref)111.00 (ref)4050.84 (0.74–0.96)111.39 (0.67–2.86)
Normal6981.19 (1.06–1.33)441.19 (0.62–2.32)5231.00 (ref)221.00 (ref)
Borderline3481.26 (1.11–1.44)811.65 (0.88–3.12)2631.05 (0.91–1.22)401.37 (0.81–2.30)
Stage 1 hypertension3361.45 (1.27–1.66)791.66 (0.88–3.13)2721.23 (1.06–1.42)781.62 (1.00–2.61)
Stage 2 hypertension681.67 (1.30–2.14)162.73 (1.26–5.92)571.46 (1.11–1.93)332.51 (1.44–4.37)
Stage 3 hypertension174.22 (2.61–6.84)32.91 (0.80–10.55)112.87 (1.58–5.23)133.60 (1.71–7.59)
p Value for trend<0.0010.002<0.001NA

NA = not available; other abbreviations as in Tables 1 and 3.

  • * Adjusted by age, BMI, cigarette smoking status, and physical activity at college entry.

  • Adjusted by age, BMI, BMI2, cigarettes per day, serum cholesterol level, electrocardiographic abnormality, race, and education. ‡Previous Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure criteria categories: optimal (<120/<80 mm Hg), normal (120–129/80–84 mm Hg), borderline (130–139/85–89 mmHg), stage 1 hypertension (140–159/90–99 mm Hg), stage 2 hypertension 160–179/100–109 mm Hg), and stage 3 hypertension (≥180/≥110 mm Hg).