Table 2

Changes of Intravascular Ultrasound Findings Between Baseline and Follow-Up

PIT (n = 62)VH-TCFA (n = 20)ThCFA (n = 93)Fibrotic (n = 22)Fibrocalcific (n = 19)
BaselineFollow-UpBaselineFollow-UpBaselineFollow-UpBaselineFollow-UpBaselineFollow-Up
Minimum lumen site
 Lumen area, mm28.2 (6.3–10.5)7.2 (5.2–9.6)7.2 (6.2–9.0)6.8 (5.6–8.3)6.8 (5.3–8.4)6.4 (4.4–8.5)7.5 (5.7–10.7)7.4 (6.1–10.7)8.1 (7.3–9.7)8.1 (6.8–19.7)
 EEM area, mm215.5 (13.0–19.5)16.1 (13.4–20.2)16.0 (14.7–18.1)15.4 (13.8–17.9)15.6 (12.8–17.9)15.5 (12.6–18.7)17.5 (12.2–19.2)17.3 (11.8–19.5)16.9 (15.8–18.8)17.1 (15.1–19.4)
 P&M area, mm27.8 (6.2–10.0)9.0 (6.5–12.0)8.6 (7.3–9.9)9.5 (7.8–10.8)8.6 (6.8–10.2)8.8 (7.1–11.4)7.9 (6.0–10.7)8.0 (6.5–11.3)9.2 (6.8–10.8)9.3 (7.2–11.0)
 Plaque burden, %47 (41–56)55 (49–62)54 (51–58)58 (53–63)55 (49–62)56 (49–67)49 (44–56)51 (47–58)53 (44–58)53 (44–62)
 DC, %1 (1–2)2 (1–4)11 (7–14)8 (5–15)11 (7–19)12 (7–16)2 (1–4)2 (1–5)24 (21–32)27 (17–35)
 NC, %8 (4–12)11 (5–21)32 (23–36)21 (15–24)22 (17–28)20 (15–26)9 (6–11)8 (6–17)22 (18–30)24 (20–29)
 FF, %21 (14–30)20 (12–26)8 (4–12)13 (11–21)10 (6–17)12 (7–20)11 (8–13)17 (9–22)7 (5–11)8 (3–11)
 FT, %67 (62–74)65 (58–69)49 (44–55)51 (47–59)53 (44–60)53 (47–60)78 (72–79)68 (61–72)42 (34–52)45 (34–51)
Volumetric analysis
 P&M volume, mm344.4 (28.9–81.3)50.8 (31.5–91.1)77.4 (48.0–104.2)82.0 (57.7–117.4)70.3 (35.1–113.2)74.4 (35.7–107.3)42.5 (20.0–65.8)44.1 (20.4–68.0)77.4 (39.8–118.9)81.2 (39.9–121.2)
 DC, %2 (1–4)4 (1–6)9 (7–12)7 (4–13)10 (6–17)11 (7–15)3 (2–4)5 (1–7)17 (9–24)14 (10–20)
 NC, %8 (5–13)10 (6–16)25 (20–29)17 (12–20)20 (14–25)19 (12–22)9 (6–12)9 (6–16)16 (11–26)19 (16–22)
 FF, %21 (17–31)22 (15–28)10 (8–13)17 (12–20)12 (9–18)14 (10–20)12 (10–14)18 (12–26)11 (4–19)13 (8–17)
 FT, %65 (59–69)63 (58–67)55 (49–58)56 (50–60)56 (49–60)55 (49–60)75 (72–79)63 (58–70)55 (43–60)55 (47–57)

Values are given as median (interquartile range).

DC = dense calcium; EEM = external elastic membrane; FF = fibrofatty; FT = fibrotic tissue; NC = necrotic core; P&M = plaque and media; PIT = pathological intimal thickening; TCFA = thin-capped fibroatheroma; ThCFA = thick-capped fibroatheroma.

  • p < 0.05 vs. baseline.