Table 1

Baseline Characteristics by Study

FRISC-II (n = 2,457)RITA-3 (n = 1,810)ICTUS (n = 1,200)
Age, yrs64.6 (9.1)62.4 (10.3)61.9 (10.6)
 <55470 (19.1%)433 (23.9%)298 (24.8%)
 55–<60179 (7.3%)263 (14.5%)210 (17.5%)
 60–<65475 (19.3%)316 (17.5%)163 (13.6%)
 65–<70567 (23.1%)295 (16.3%)176 (14.7%)
 70–<75305 (12.4%)277 (15.3%)201 (16.8%)
 75+461 (18.8%)226 (12.5%)152 (12.7%)
Weight, kg79.6 (13.5)78.6 (14.6)81.5 (12.9)
BMI, kg/m226.8 (3.8)27.7 (4.7)27.1 (3.7)
Sex
 Women749 (30.5%)682 (37.7%)320 (26.7%)
 Men1,708 (69.5%)1,128 (62.3%)880 (73.3%)
Smoking
 Current745 (30.3%)586 (32.4%)492 (41.0%)
Hypertension743 (30.2%)632 (34.9%)466 (38.8%)
Hyperlipidemia262 (10.7%)579 (32.0%)417 (34.8%)
Diabetes299 (12.2%)244 (13.5%)166 (13.8%)
Previous MI546 (22.2%)501 (27.7%)278 (23.2%)
Previous PCI80 (3.3%)93 (5.1%)140 (11.7%)
Previous CABG9 (0.4%)0 (0.0%)105 (8.8%)
ST-segment depression1,152 (47.1%)660 (36.5%)513 (44.6%)
ST-segment elevation202 (8.3%)139 (7.7%)137 (11.9%)
ST-segment deviation1,240 (50.7%)742 (41.0%)574 (50.0%)

Values are mean (SD) or n (%). In total, of those discharged alive, 62.0% were discharged on a statin (RI: 61.9%, SI: 62.1%), 93.2% on aspirin (RI: 92.4%, SI: 94.0%), 80.6% on a beta-blocker (RI: 78.6%, SI: 82.6%), and 22.7% on an angiotensin-converting enzyme inhibitor (RI: 22.4%, SI: 22.9%).

BMI = body mass index; CABG = coronary artery bypass graft; FRISC-II = Fragmin and Fast Revascularization during Instability in Coronary Artery Disease; ICTUS = Invasive Versus Conservative Treatment in Unstable Coronary Syndromes; MI = myocardial infarction; PCI = percutaneous coronary intervention; RI = routine invasive; RITA-3 = Randomized Trial of a Conservative Treatment Strategy Versus an Interventional Treatment Strategy in Patients with Unstable Angina; SI = selective invasive.

  • For assessing differences in baseline characteristics across the 3 studies, p < 0.001 for each variable except diabetic status (p = 0.27).