Table 1

Baseline Demographics and Medical History by Years of Education

Years of Education
Characteristics<8 yrs (n = 2,249)8–12 yrs (n = 6,982)>12–16 yrs (n = 1,633)>16 yrs (n = 462)p Value
Demographics
 Age (yrs)67.9 (60.0, 74.9)62.1 (52.6, 70.6)58.3 (49.6, 68.3)57.7 (50.6, 67.5)<0.0001
 Female sex666 (29.6)2,021 (28.9)348 (21.3)61 (13.2)<0.0001
 White race2,131 (94.8)6,625 (94.9)1,510 (92.5)408 (88.5)0.0030
 Height (cm)170 (163, 175)172 (165, 177)173 (167, 180)175 (168, 180)<0.0001
 Weight (kg)75 (67, 84)78 (70, 89)80 (72, 90)80 (73, 91)<0.0001
Medical history
 Hypertension838 (37.3)2,677 (38.4)637 (39.0)194 (42.0)0.9389
 Diabetes mellitus374 (16.6)1,052 (15.1)230 (14.1)59 (12.8)<0.0001
 Current smoking795 (35.8)3,029 (43.5)667 (40.9)156 (33.9)<0.0001
 Elevated cholesterol545 (24.5)2,459 (35.4)636 (39.0)190 (41.2)0.0008
 Previous CHF76 (3.4)175 (2.5)30 (1.8)7 (1.5)<0.0001
 Previous MI499 (22.2)1,275 (18.3)281 (17.2)59 (12.8)0.0008
 Previous cerebrovascular disease64 (2.8)170 (2.4)29 (1.8)15 (3.2)0.3718
 Previous PCI61 (2.7)353 (5.1)100 (6.1)31 (6.7)<0.0001
 Previous CABG72 (3.2)260 (3.7)71 (4.3)16 (3.5)0.0002
No. of patients by country of enrollment
 United Kingdom522794893
 Germany221937832
 Sweden6023477616
 Italy2751357327
 New Zealand15325302
 Poland1323966433
 Canada1641104309129
 Australia153727489
 United States1652217861241

Data are presented as median (25th, 75th percentile) or n (%) unless otherwise noted.

CABG = coronary artery bypass graft; CHF = congestive heart failure; MI = myocardial infarction; PCI = percutaneous coronary intervention.