Table 2

Multivariate Association Between Level of Renal Function and the Risk for Presentation of CHD as Acute Myocardial Infarction Versus Stable Exertional Angina

Adjusted Odds Ratio (95% Confidence Interval)
eGFR (ml/min/1.73 m2)Model 1Model 2Model 3Model 4§Model 5
90–130ReferentReferentReferentReferentReferent
60–891.25 (0.96–1.63)1.30 (0.98–1.73)1.33 (1.00–1.78)1.31 (0.98–1.80)1.36 (1.00–1.86)
45–591.27 (0.81–1.97)1.38 (0.86–2.21)1.34 (0.84–2.16)1.34 (0.82–2.19)1.55 (0.91–2.62)
<452.58 (1.16–5.75)2.77 (1.21–6.34)2.64 (1.15–6.10)2.71 (1.16–6.34)3.82 (1.55–9.46)

CHD = coronary heart disease; eGFR = estimated glomerular filtration rate.

  • eGFR only.

  • Model 1 plus age, sex, race or ethnicity, family history of CHD, cigarette smoking history, and physical activity level.

  • Model 2 plus prior stroke or peripheral artery disease, diabetes mellitus, and hypertension.

  • § Model 3 plus systolic blood pressure, body mass index, and prior low-density lipoprotein and high-density lipoprotein cholesterol levels.

  • Model 4 plus prior use of statins, beta-blockers, calcium-channel blockers, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and diuretic agents.