Table 1

Baseline Characteristics of Adults With Acute Myocardial Infarction or Stable Exertional Angina as the First Presentation of CHD

CharacteristicAcute Myocardial Infarction (n = 803)Stable Exertional Angina (n = 419)p Value
Prior eGFR (ml/min/1.73 m2)
 Mean ± SD78.2 ± 18.781.2 ± 17.90.006
 Median (interquartile range)78.0 (66.0–90.0)80.0 (70.0–92.0)0.006
Category of prior eGFR (ml/min/1.73 m2)0.07
 90–13026.5%31.7%
 60–8959.5%57.0%
 45–599.8%9.3%
 <454.1%1.9%
Age (yrs)62.5 ± 8.462.1 ± 8.40.35
Women23.8%33.7%<0.001
Race/ethnicity0.68
 White European/Middle Eastern67.8%69.5%
 African American4.6%3.3%
 Hispanic/Latino9.6%11.0%
 South Asian2.1%1.2%
 Asian/Pacific Islander5.4%5.0%
 Native American0.0%0.0%
 Non-Hispanic admixed10.6%10.0%
Annual household income0.28
 <$25,00013.2%11.5%
 $25,000–$49,99925.0%25.1%
 $50,000–$99,99939.3%35.4%
 >$100,00015.6%19.6%
 Refused to answer7.0%8.4%
Marital status0.46
 Married/domestic partner72.6%76.4%
 Divorced/separated14.3%12.5%
 Widowed8.2%6.3%
 Never married5.0%4.8%
Cigarette smoking0.01
 Current9.7%6.7%
 Former55.5%50.6%
 Never34.8%42.7%
Alcohol use in prior 12 months67.7%73.3%0.04
Leisure-time activity in past 12 months<0.001
 Minimal34.0%30.0%
 Light20.8%12.7%
 Moderate32.5%39.8%
 Heavy12.8%17.5%
Medical history
 Stroke/transient ischemic attack10.0%11.2%0.51
 Peripheral artery disease10.5%8.8%0.35
 Diabetes mellitus29.0%24.6%0.10
 Diagnosed hypertension83.4%76.1%0.002
Parental history of coronary heart disease46.8%57.5%<0.001
Sibling history of coronary heart disease21.2%27.2%0.02
Medication use within 160 days before event
 Statins21.9%41.3%<0.001
 Niacin0.9%0.7%0.77
 Cholestyramine0.4%0.7%0.42
 Colestipol0.1%0.5%0.24
 Colesevelam0.0%0.0%NA
 Gemfibrozil1.6%2.6%0.23
 Fenofibrate0.1%0.7%0.09
 Beta-blockers21.1%48.4%<0.001
 Calcium-channel blockers14.7%10.3%0.03
 Alpha-blockers2.2%1.2%0.20
 ACE inhibitors22.7%27.0%0.10
 ARBs3.2%3.8%0.60
 Diuretic agents21.5%24.6%0.23
 Hormone replacement therapy31.9% (of 191 women)36.9% (of 141 women)0.35
Blood pressure at most recent outpatient visit before index date
 Systolic (mm Hg)(n = 714)(n = 389)0.05
  ≤12016.5%22.9%
  121–12912.8%15.7%
  130–13927.9%23.9%
  140–15931.4%26.5%
  160–1799.1%9.3%
  >1802.4%1.8%
 Diastolic (mm Hg)(n = 714)(n = 390)<0.001
  ≤8055.5%67.2%
  81–8416.8%10.5%
  85–8911.6%7.7%
  90–9911.8%11.3%
  100–1093.6%1.0%
  ≥1100.7%2.3%
Body mass index (kg/m2)29.3 ± 5.529.0 ± 4.80.31
Category of body mass index (kg/m2)0.74
 <2520.2%19.7%
 25–2942.6%44.8%
 ≥3037.2%35.5%
Prior lipoprotein testing and results
 Total cholesterol (mg/dl)221.6 ± 39.5217.8 ± 41.30.13
  Tested95.3%97.6%0.05
 LDL cholesterol (mg/dl)137.0 ± 34.3131.7 ± 35.40.02
  Tested82.2%91.0%<0.001
 HDL cholesterol (mg/dl)45.1 ± 12.547.1 ± 13.10.01
  Tested91.8%96.4%0.002
 Triglycerides (mg/dl)195.0 ± 115.6198.9 ± 126.70.62
  Tested82.9%91.4%<0.001

Values are mean ± SD median (interquartile range), or %.

ACE = angiotensin converting enzyme; ARB = angiotensin receptor blocker; CHD = coronary heart disease; HDL = high-density lipoprotein; LDL = low-density lipoprotein; NA = not applicable.