Table 3

Echocardiographic and Clinical Parameters at Baseline and Follow-Up Between Both Randomized Groups

Target (n = 103)Control (n = 104)p Value
NYHA functional class
 Baseline3.1 ± 0.33.1 ± 0.3
 Follow-up2.0 ± 0.72.3 ± 0.7
 Change−1.1 ± 0.7−0.8 ± 0.70.002
6MWT, m
 Baseline222 ± 92229 ± 95
 Follow-up282 ± 101268 ± 112
 Change61 ± 7638 ± 760.011
MLHFQ
 Baseline55 ± 2153 ± 20
 Follow-up33 ± 2138 ± 22
 Change−22 ± 20−16 ± 190.024
LVEDV, ml
 Baseline202 ± 66200 ± 58
 Follow-up160 ± 51176 ± 56
 Change−41 ± 34−23 ± 230.001
LVESV, ml
 Baseline157 ± 56154 ± 52
 Follow-up111 ± 43128 ± 50
 Change−46 ± 33−26 ± 230.001
LVEF, %
 Baseline23 ± 623 ± 7
 Follow-up31 ± 928 ± 10
 Change8 ± 75 ± 80.001

Values are mean ± SD.

6MWT = 6-min walk test; MLHFQ = Minnesota Living With Heart Failure Questionnaire; other abbreviations as in Table 1.