Table 2

PR (in PRU) at the End-of-Treatment Periods

EndpointnTicagrelor Least Squares Estimates (95% CI)nPrasugrel Least Squares Estimates (95% CI)nLeast Squares Mean Difference (95% CI)p Value
PR day 15 (pre-crossover)4334.1 (15.1 to 53.1)2190.8 (72.3 to 109.4)22−56.7 (−83.3 to −30.2)<0.001
PR day 30 (post-crossover)4232.1 (10.5 to 53.6)22111.4 (88.7 to 134.1)20−79.3 (−110.6 to −48.0)<0.001
Combined data (pre- and post-crossover)8532.9 (18.7 to 47.2)43101.3 (86.8 to 115.7)42−68.3 (−88.6 to −48.1)<0.001

CI = confidence interval; PR = platelet reactivity; PRU = platelet reactivity unit(s).