Table 6

Tabulation in Clinical Trials of MI Types According to Multiples of the 99th Percentile Upper Reference Limit of the Applied Cardiac Biomarker

Multiples × 99%Ml type 1 SpontaneousMl type 2 SecondaryMl type 3 DeathMl type 4a PCIMl type 4b Stent-ThrombusMl type 4c RestenosisMl type 5 CABG
1–3
3–5
5–10
>10
Total

MI = myocardial infarction; PCI = percutaneous coronary intervention; CABG = coronary artery bypass grafting.

Red areas indicate arbitrarily defined cTn values below the MI decision limit whether PCI or CABG.

  • Biomarker values are unavailable because of death before blood samples are obtained (blue area).

  • Restenosis is defined as ≥50% stenosis at coronary angiography or a complex lesion associated with a rise and/or fall of cTn values >99th percentile URL and no other significant obstructive CAD of greater severity following: (i) initially successful stent deployment or (ii) dilatation of a coronary artery stenosis with balloon angioplasty (<50%).