Table 3

Biventricular Versus Univentricular Stimulation Clinical Effects

Clinical MeasureBiventricularTreatmentUniventricularTreatment*pValue
Oxygen uptake at peak exercise (ml/kg/min)14.91 ± 0.6614.58 ± 0.770.324
Oxygen uptake at anaerobic threshold (ml/kg/min)10.70 ± 0.4710.39 ± 0.510.290
6-min walk distance (m)402 ± 16401 ± 160.345
Quality-of-life score25.2 ± 3.328.1 ± 3.50.069
NYHA functional class0.360
 IV2 (5%)3 (7%)
 III17 (41%)14 (34%)
 II16 (39%)15 (37%)
 I6 (15%)9 (22%)

NYHA = New York Heart Association.

  • * Left ventricular stimulation in 36 patients and right ventricular stimulation in 4 patients.

  • All p values were derived from the F test for treatment method effects following analysis of variance, except for NYHA functional class, which was derived from the Wilcoxon matched-pairs test. Data are presented as the mean value ± SEM or number (%) of subjects.