Table 3

Summary Estimates of Event Rates After a Negative Test and Negative Predictive Values for MI and Cardiac Death, and Revascularization and Unstable Angina After a Negative Test

Exercise Imaging Modality and EventsnMean Follow-Up (Months)Mean Age (yrs)Women (%)Summary Event Rate After a Negative Test (%) (95% CI)Negative Predictive Value (%) (95% CI)Annualized Event Rate (%)
MI and cardiac death
 MPI8,0083654341.21 (0.98–1.48)98.8 (98.5–99.0)0.45
 Thallium8684557323.11 (2.05–4.53)96.9 (95.5–97.9)0.70
 Sestamibi1,8023258351.28 (0.81–1.92)98.7 (98.1–99.2)0.34
 Thallium/sestamibi4,9382361390.83 (0.60–1.13)99.2 (98.9–99.4)0.45
 Tetrofosmin4004357281.5 (0.55–3.26)98.5 (96.8–99.4)0.42
 Echo3,0213356461.56 (1.14–2.07)98.4 (97.9–98.9)0.54
Revascularization and unstable angina
 MPI1,7563652363.42 (2.61–4.40)96.6 (95.6–97.4)1.25
 Echo3803254452.63 (1.26–4.84)97.4 (95.2–98.7)0.95

Echo = echocardiography; MPI = myocardial perfusion imaging; other abbreviations as in Table 1.